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NCT06931886

Pulmonary Hypertension Inspiratory Training

Enrolling by Invitation
NAAges 18+InterventionalSupportive care
University of Arizona
~4 participants
Updated 2025-12-17 on ClinicalTrials.gov
What's tested:Inspiratory Muscle Strength Training

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pulmonary arterial pressure
Measured over The data will be obtained from previous medical records of patient visits occurring up to 8 months prior to enrollment and at the end of treatment at 6 weeks post enrollment. .
+2 more outcomes measured

Conditions

Pulmonary Hypertension

Explore related trials

Pulmonary Hypertension

Where it's being run

1 sites across 1 states
Arizona1

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Diagnosed with PH defined by clinical guideline criteria
Must already be scheduled for a clinical assessment of their PH within 8 weeks of enrolling in the study.
Must have undergone an assessment of their PH in the last 18 months with no major changes in PH management or medication within that period.

Exclusion

Current smoker or have smoked in the last 10 years
Unable or unwilling to undergo routine functional testing of their PH (i.e., 6-minute walk distance).
Presence of significant cardiovascular or respiratory conditions other than PH, including but not limited to:
Chronic obstructive pulmonary disease
Severe asthma
Severe ischemic heart disease
Left-sided heart failure
History of a major cardiovascular event, such as a myocardial infarction or stroke, within the last 6 months
Individuals with an implanted pacemaker or other significant cardiac devices
History of neurological, respiratory, head and neck, or thoracic surgeries, or conditions such as a collapsed lung or perforated eardrum
Pregnant individuals or those actively trying to become pregnant
Individuals with any of the following: chronic laryngitis, chronic bronchitis, emphysema, pneumonia, tuberculosis, chronic cough, extremely high blood pressure (\>170/100), neurological problems, scoliosis, organ transplants, HIV or other immunocompromising conditions, or autoimmune disease.

What this trial measures

  • Pulmonary arterial pressureThe data will be obtained from previous medical records of patient visits occurring up to 8 months prior to enrollment and at the end of treatment at 6 weeks post enrollment. .

    To be eligible for this study, patients must already have an upcoming invasive cardiopulmonary exercise test scheduled for assessment of their PH. Pulmonary arterial pressure will be obtained from this upcoming appointment as well as from previous medical records and an upcoming already scheduled assessment of pulmonary hypertension.

  • Cardiac OutputThe data will be obtained from previous medical records of patient visits occurring up to 8 months prior to enrollment and at the end of treatment, which occurs 6 weeks post-initiation.

    This will be obtained as part of the usual standard assessment of pulmonary hypertension. Patients must already have this scheduled prior to enrollment in this study. Cardiac output, a measure of the volume of blood the heart pumps per minute, will be determined at rest and in response to exercise during the scheduled cardiopulmonary exercise test. This involves a graded maximal cycling protocol on a stationary bike, where resistance progressively increases until the patient reaches their maximum effort or exhaustion .

  • Maximal Oxygen UptakeThe data will be obtained from previous medical records of patient visits occurring up to 8 months prior to enrollment and at the end of treatment at 6 weeks post enrollment. .

    This will be obtained as part of the usual standard assessment of pulmonary hypertension. Patients must already have this scheduled prior to enrollment in this study. Maximal oxygen uptake, a measure of the body's maximum ability to take in, transport, and utilize oxygen during intense exercise, will be determined during the scheduled cardiopulmonary exercise test. This test involves a graded maximal cycling protocol on a stationary bike, where resistance progressively increases until the patient reaches their maximum effort or exhaustion. Throughout the test, patients will wear a mask that is used to analyze gas exchange.