Observational Study of Brain Blood Flow in Subarachnoid Hemorrhage
This observational study aims to understand how blood flow to the brain changes in patients who have experienced a subarachnoid hemorrhage (SAH), which is bleeding on the surface of the brain. Researchers will use a non-invasive device called Near-Infrared Spectroscopy (NIRS) (HEM1 with Foresight Elite Sensor) to continuously monitor brain oxygen levels. The main goal is to see if the ideal blood pressure for the brain changes over time in SAH patients, and if problems with the brain's ability to regulate its own blood flow contribute to delayed brain injury. This study is for patients aged 18 to 89 who are admitted to the Neuro ICU for aneurysmal SAH between March 2025 and December 2026. The study will measure changes in the Lower Limit of Autoregulation (LLA) over 21 days.
- Study design
- This is an observational study involving 120 participants. It is not testing a new treatment but rather observing how the brain's blood flow regulation changes in patients with subarachnoid hemorrhage.
- What's involved
- You would have a non-invasive NIRS device connected, which automatically captures brain oxygen data and stores it. The study will measure changes over 21 days.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured at 21 days, indicating monitoring for at least that duration.
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Continuous Assessment of Brain Blood Perfusion in Subarachnoid Hemorrhage Patients Using Near-Infrared Spectroscopy (NIRS)
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Weifeng Song, M.D., Ph.D · PRINCIPAL_INVESTIGATOR · The University of Alabama at Birmingham
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Do you actually qualify for this trial?
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What this trial measures
- Change in Lower Limit of Autoregulation (LLA)21 days
Successful calculations of moving Lower Limit of Autoregulation (LLA) for all three algorithms