Study of Microprocessor-Controlled Prosthetic Knees for Above-Knee Amputees

This study is looking at whether microprocessor-controlled prosthetic knees (MPKs), which have a built-in computer, can help people with above-knee amputations who use prostheses. Specifically, it wants to see if using an MPK like the Ottobock C-Leg 4 or Ottobock Kenevo can reduce fall-related health problems, improve walking, and increase quality of life compared to standard prosthetic knees. You might be able to join if you are an adult with a single above-knee amputation, have been using a prosthesis for at least six months, and currently use a non-microprocessor knee. The study will measure how you feel about falls, your anxiety about falling, and behaviors you might use to avoid falls over 12 months to see if the MPKs are helpful. The study is currently unclear on its recruitment status and plans to enroll 100 participants.

Study design
This is a 12-month randomized controlled trial, meaning participants will be randomly assigned to either receive a microprocessor-controlled knee or continue using their current non-microprocessor knee. The study plans to enroll 100 participants.
What's involved
You would participate in assessments at baseline, 1 month, 3 months, 6 months, 9 months, and 12 months. You would either continue using your current non-microprocessor knee or receive an Ottobock C-Leg 4 or Ottobock Kenevo prosthetic knee.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06937242

Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators

Recruiting
NAAges 18+InterventionalSupportive care
Hanger Institute for Clinical Research and Education, LLC
~100 participants
Updated 2026-02-05 on ClinicalTrials.gov
What's tested:Ottobock C-Leg 4 Microprocessor KneeOttobock Kenevo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Prosthetic Limb Users Survey of Fall-Related Self-Efficacy (PLUS-F-SEF)
Measured over Collected at baseline, 1-month, 3-month, 6-month, 9-month, and 12-month assessments.
+4 more outcomes measured
Amputation
Prosthesis User
Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Limb; Absence, Congenital, Lower
Lower Limb Amputation Above Knee (Injury)
Lower Limb Amputation Above Knee

NCT06937242

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Hanger Inc.

    Austin, Texasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Shane R. Wurdeman, PhD · PRINCIPAL_INVESTIGATOR · Hanger Institute for Clinical Research and Education

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Unilateral transfemoral or knee disarticulation limb loss.
6 months or longer since time of limb loss.
Current user of a prosthesis with a non-microprocessor-controlled prosthetic knee.
Received a replacement prosthesis with a non-microprocessor knee in the past 4-24 months.
Clinician has deemed patient limited community ambulator (Medicare functional classification level K2).
In addition, Medicare functional classification level K2 as determined by at least one of the following criteria:
Ability to read, write, and understand English.

Exclusion

Any health condition that would prevent safely completing trial activities.
Any individuals that weigh 275 lbs or more.
Any individuals who wear their prosthesis less than 3 days a week or less than a total of 24 hours a week
Individuals with a history of acute or chronic residual limb breakdown
Individuals with declining health status such that he/she subsequently reports reduced activity over the past 6 months
  • Prosthetic Limb Users Survey of Fall-Related Self-Efficacy (PLUS-F-SEF)Collected at baseline, 1-month, 3-month, 6-month, 9-month, and 12-month assessments.

    The PLUS-F-SEF is a 15-item self-report instrument we developed in the present study to measure perceived ability to avoid a loss of balance while performing an activity. Respondents rate their degree of confidence on a 5-point scale from "not at all confident" (1) to "very much confident" (5). A standardized T-score is generated for the PLUS-F-SEF using a lookup table that converts the raw score to a T-score.

  • Prosthetic Limb Users Survey of Fall-Related Anxiety (PLUS-F-ANX)Collected at baseline, 1-month, 3-month, 6-month, 9-month, and 12-month assessments.

    The PLUS-F-ANX is a 15-item self-report instrument we developed in the present study to measure perceived apprehensions or concerns about losing one's balance or falling. Respondents rate the frequency with which they experience various emotional responses on a 5-point scale from "never" (1) to "always" (5). A standardized T-score is generated for the PLUS-F-ANX using a lookup table that converts the raw score to a T-score.

  • Prosthetic Limb Users Survey of Fall-Related Avoidance Behaviors (PLUS-F-AVB)Collected at baseline, 1-month, 3-month, 6-month, 9-month, and 12-month assessments.

    The PLUS-F-AVB is a 15-item self-report instrument we developed in the present study to measure perceived changes in the manner or frequency with which activities are performed to avoid losing one's balance or falling. Respondents rate the frequency with which they make changes on a 5-point scale from "never" (1) to "always" (5). A standardized T-score is generated for the PLUS-F-AVB using a lookup table that converts the raw score to a T-score.

  • Prosthetic Limb Users Survey of Fall-Related Interference (PLUS-F-INT)Collected at baseline, 1-month, 3-month, 6-month, 9-month, and 12-month assessments.

    The PLUS-F-INT is a 15-item self-report instrument we developed in the present study to measure perceived restrictions in social, cognitive, emotional, and/or physical life situations due to risk of falls. Respondents rate the amount of interference on a 5-point scale from "not at all" (1) to "very much" (5). A standardized T-score is generated for the PLUS-F-INT using a lookup table that converts the raw score to a T-score.

  • Number of Reported Falls and Near-Fall EventsCollected every two weeks starting at baseline up to 12 months

    Participants will be contacted every 2 weeks starting at baseline through study completion to determine whether they experienced a fall event (either a fall or near-fall). For each event experienced, participants will be asked to report the details of that event using the Lower Limb Prosthesis User Fall Event Survey we developed in a prior study. This instrument asks respondents to report the activity, surroundings, situation, mechanics, and consequences of each event. Fall events will be scored as the total number of falls, near-falls, and all fall events experienced. The details of the events are descriptive in nature and will be used to characterize the falls experienced by the participant.