Bumetanide vs. Furosemide in Cirrhosis

This study is comparing two common medications, bumetanide and furosemide, which are both diuretics (water pills) used to treat fluid buildup in patients with cirrhosis (severe liver scarring). The researchers want to see how well each medication helps reduce fluid by measuring changes in your weight over 7 days. You might be able to join if you have cirrhosis and your doctor has ordered either bumetanide or furosemide for you within 24 hours of coming to the hospital. The study aims to enroll 500 participants, but its current recruitment status is unclear.

Study design
This interventional study plans to enroll 500 participants. It compares two standard treatments, bumetanide and furosemide, given as ordered by your doctor.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your weight will be measured at 7 days to see how well the treatment is working.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06941415

Bumetanide vs. Furosemide in Cirrhosis

Recruiting
PHASE3Ages 18+InterventionalTreatment
Stacy Johnson
~500 participants
Updated 2026-06-16 on ClinicalTrials.gov
What's tested:BumetanideFurosemide

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percent change in weight
Measured over 7 days
Cirrhosis
1 sites across 1 states
Utah1
  • Stacy A Johnson, MD · PRINCIPAL_INVESTIGATOR · University of Utah

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Eligibility criteria

Inclusion

History of liver cirrhosis
Clinician placed an order for bumetanide or furosemide in electronic health record within 24 hours of presentation to the hospital

Exclusion

Allergy to bumetanide or furosemide
Contraindication to diuretic administration (e.g. active bleeding, clinical suspicion of hepatorenal syndrome, hypotension)
Incarcerated or in custody of law enforcement
Diuretic ordered for purpose other than volume overload (e.g. hyperkalemia, continuation of home medication without clinical signs of volume overload)
Inpatient admission not anticipated
Not admitted to an inpatient hospital bed following initial evaluation in the emergency department
  • Percent change in weight7 days

    Percent change in weight measured in kilograms from date of emergency department presentation (Day 0) to Day 7 of hospitalization, or date of discharge, whichever is earlier