Huntington's Disease Biobank: Advancing Remote Monitoring and Deep Phenotyping

This observational study is looking for people with Huntington's disease (HD) to help researchers understand how the disease starts and changes over time. It uses a combination of remote monitoring tools like computer vision (analyzing videos of movement), mobile apps for thinking skills, and wearable wrist bands. You would also provide blood and urine samples. The goal is to find new ways to track HD progression from your home, making it easier to evaluate symptoms. Researchers will track your disease progression and compare these digital markers with changes in your blood and cerebrospinal fluid. The study plans to enroll 200 participants.

Study design
This is an observational study, meaning it watches and collects information without giving a specific treatment. It aims to enroll 200 participants.
What's involved
You would have an in-person evaluation once a year and remote evaluations three times a year. You would also provide blood and urine samples, and use wrist bands and a mobile app.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed until death or dropout, with an average follow-up of approximately one year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06941662

Huntington's Disease Biobank: Advancing Remote Monitoring and Deep Phenotyping

Recruiting
Not specifiedAll AgesObservational
Stanford University
~200 participants
Updated 2025-04-24 on ClinicalTrials.gov
What's tested:computer vision, remote monitoring, blood, urine, wrist bands, mobile-app

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Unified Huntington's Disease Rating Scale (UHDRS)
Measured over Once a year in-person and 3 times a year remotely, until death or dropout of the study (average approximately 1 year)
Huntington Disease

NCT06941662

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Stanford University

    Palo Alto, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Kyan Younes, MD · PRINCIPAL_INVESTIGATOR · Stanford University

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Eligibility criteria

Inclusion

Individuals with a positive test for the HD expansion mutation.

Exclusion

Individuals with movement disorders with a negative test for the HD expansion mutation.
  • Unified Huntington's Disease Rating Scale (UHDRS)Once a year in-person and 3 times a year remotely, until death or dropout of the study (average approximately 1 year)

    Neurological exam with a neurologist to document the motor exam