This study is looking at how well oral wounds heal after a tooth extraction, especially in older individuals, when a product called Platelet-Rich Fibrin (PRF) is used. PRF is made from your own blood and is placed in the tooth socket after extraction. Researchers want to see if PRF helps the healing process. They will measure cytokine concentration (proteins that help with healing) at the beginning and two weeks after the extraction. This study plans to enroll 12 participants, aged 14 to 80, who need a back tooth removed at the University of Nebraska Medical Center College of Dentistry. The study is currently unclear on its recruitment status.

Study design

This interventional study will involve 12 participants. Six will be aged 14-18 and six will be aged 50-80.

What's involved

You would have a posterior tooth extraction, provide a small tissue sample, and potentially have blood drawn for PRF. You would return in 2 weeks for suture removal and another tissue sample, and at 3 months for a final X-ray.

Compensation

Not stated in the trial record.

Follow-up

Participants will have a final post-operative radiograph at 3 months after the extraction.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.