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Pilot Study for Precision Exercise Regimen in Lung Cancer

This pilot study, called PERCC, is testing if a special exercise program is practical for people with stage II or III non-small cell lung cancer (NSCLC). This program, called the Precision Exercise Regimen for Cancer Care (PERCC), includes different types of exercises like mobility, aerobic, and strength training, done in various positions and challenges. You can join if you are 18 or older, have stage II or III NSCLC, are receiving chemotherapy or immunotherapy and surgery, can follow directions in English or Spanish, and agree to do the PERCC exercises. The main goal is to see how easy it is to recruit and keep people in the study, measured up to two months after surgery. This study is currently unclear on its recruitment status and plans to enroll 20 participants.

Study design
This is a pilot study designed to evaluate the feasibility of the PERCC intervention. It plans to enroll 20 participants with stage II or III non-small cell lung cancer.
What's involved
You would participate in a virtually supervised home-based exercise program, starting at least two weeks before your first cancer treatment and continuing until two months after surgery.
Compensation
Not stated in the trial record.
Follow-up
You will be followed until approximately two months post-surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06945484

PILOT for The Precision Exercise Regimen for Cancer Care (PERCC) Study

Recruiting
NAAges 18+InterventionalTreatment
University of Utah
~20 participants
Updated 2026-02-03 on ClinicalTrials.gov
What's tested:Precision Exercise Regimen for Cancer Care (PERCC)

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility - Recruitment and Retention
Measured over up to two months post-surgery

Conditions

NSCLC Stage II
NSCLC, Stage III

Explore related trials

Lung Non-Small Cell Carcinoma

Where it's being run

2 sites across 2 states
Texas1
Utah1

Study leadership

  • Cornelia Ulrich, MS, PhD · PRINCIPAL_INVESTIGATOR · Huntsman Cancer Institute

Who to contact

Thomas Varghese, MD, MS, MBA, FACS
[email protected]
801-581-5311
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Ages 18 and older at time of diagnosis
Patient diagnosed with stage II and III non-small cell lung cancer (NSCLC)
Patient receives either neoadjuvant chemotherapy or immunotherapy and surgery
Patient able to follow direction and complete questionnaires in English or Spanish
Patient agrees to complete the PERCC intervention

Exclusion

Morbidly obese (BMI \>40 kg/m2 ) or anorexic (BMI \<17.5 kg/m2 )
Abnormalities on screening physical exam per study physicians or physical therapist to contraindicate participation in exercise program compliance
Alcohol or drug abuse, significant mental or emotional problems that would interfere with compliance (assessed by NCCN Distress Thermometer)
Patient scheduled to receive single modality cancer treatment (unimodal therapy), scheduled to begin treatment within 2 weeks of the pre-treatment clinic visit, or for whom treatment has already started

What this trial measures

  • Feasibility - Recruitment and Retentionup to two months post-surgery

    Feasibility of the PERCC intervention will be evaluated by our ability to recruit and retain the needed number of patients with 80% exercise intervention attendance.