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NCT06952257

Relationship Between Anesthetic Regimen and Bone Cement Implantation Syndrome (BCIS)

Enrolling by Invitation
NAAges 18+InterventionalPrevention
Johns Hopkins University
~24 participants
Updated 2026-07-21 on ClinicalTrials.gov
What's tested:Administration of general anaesthesiaNeuraxial Analgesia

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of Participants with Hypoxia
Measured over Intra-operatively, approximately 10 minutes

Conditions

Bone Cement Implantation Syndrome

Explore related trials

Bone Cement Implantation SyndromeHip Fracture

Where it's being run

1 sites across 1 states
Maryland1

Study leadership

  • Adam S. Levin, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins Hospital, Dept Orthopedic Surgery, Baltimore, MD 21287

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients \>18 years old that are indicated for cemented hemiarthroplasty for hip fracture.

Exclusion

Patients with medical comorbidities that preclude randomization to an anesthetic regimen (e.g., severe aortic stenosis contraindicating general anesthesia or therapeutic anticoagulation contraindicating neuraxial anesthesia) or
a severe cognitive impairment that precludes the ability to provide informed consent.

What this trial measures

  • Number of Participants with HypoxiaIntra-operatively, approximately 10 minutes

    Grade 1 BCIS, defined as moderate intraoperative hypoxia (\<94%) or drop in systolic blood pressure of \>20%) intraoperatively. Grade 2 BCIS, defined as severe hypoxia (\<88%) or drop in systolic hypotension \>40%. Grade 3 BCIS, defined as cardiovascular collapse requiring cardiopulmonary resuscitation.