Tivdak® for Recurrent or Metastatic Cervical Cancer: Eye Side Effects Study

This study is looking at the eye-related side effects of Tivdak®, a medicine used to treat cervical cancer that has returned or spread after chemotherapy (a treatment using medicines to stop cancer cell growth). You may be able to join if you are an adult woman with recurrent or metastatic cervical cancer, and your doctor believes Tivdak® is a suitable treatment for you. You should not have received Tivdak® before and should not have active eye problems. The study aims to understand the types, frequency, and severity of eye side effects up to 90 days after your last dose of Tivdak®. About 100 participants are planned for this study.

Study design
This is an interventional study planning to enroll 100 participants. It focuses on understanding side effects of Tivdak®.
What's involved
You will receive Tivdak® as an infusion into your vein once every 3 weeks. You must be willing to take all required eye tests.
Compensation
Not stated in the trial record.
Follow-up
Your eye side effects will be measured for 90 days after your last dose of Tivdak®.

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NCT06952660

Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer

Recruiting
PHASE4Ages 18+Interventional
Pfizer
~100 participants
Updated 2026-08-17 on ClinicalTrials.gov
What's tested:TIVDAK

At a glance

Recruiting sites
121 of 129 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Type, incidence and severity of ocular adverse events (AEs)
Measured over 90 days after the last dose of tisotumab vedotin
Cervical Cancer
129 sites across 22 states
Florida30
Ohio15
Texas14
Arizona9
Georgia7
Louisiana7
Minnesota6
Pennsylvania6
  • Pfizer CT.gov Call Center · STUDY_DIRECTOR · Pfizer

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  • Type, incidence and severity of ocular adverse events (AEs)90 days after the last dose of tisotumab vedotin