Understanding Treatments for Pediatric PTSD
This study is testing different ways to help children and teenagers (ages 8-17) who have Post-traumatic Stress Disorder (PTSD) after experiencing a traumatic event. Researchers want to see which treatment parts work best and how they help. The treatments being studied include Emotion Regulation, Exposure, Cognitive Processing, and Bi-lateral Stimulation. There's also a Psychological Placebo, which is supportive therapy without focusing on past trauma. The study will measure changes in PTSD symptoms using questionnaires like the CAPS-CA, CPSS, and CATS-2 at the beginning and after 19 weeks of treatment. To join, you must be 8-17 years old, have PTSD from a trauma, and have a caregiver's permission. The current status of the study is unclear, and it plans to enroll 200 participants.
- Study design
- This interventional study will compare different combinations of behavioral therapies to a psychological placebo. It plans to enroll 200 participants.
- What's involved
- You will receive different combinations of treatments and attend weekly treatment sessions. You will also provide information to help evaluate changes in PTSD symptoms.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your PTSD symptoms will be measured at the beginning of the study and again after 19 weeks of treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Chad E Shenk, PhD · PRINCIPAL_INVESTIGATOR · University of Rochester
Who to contact
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What this trial measures
- Mean Change in PTSD Symptoms - Clinician Administered PTSD Scale for DSM-5 - Child/Adolescent Version (CAPS-CA)Baseline (pre-treatment), Week 19 (post-treatment)
The CAPS-CA is a clinician-administered diagnostic interview measuring the severity of PTSD symptoms in the past month. The interview assesses 20 PTSD symptoms according to DSM-5 diagnostic criteria with each symptom rated on a severity scale ranging from 0 to 4. Ratings for each individual symptom are summed with higher scores indicating greater severities of PTSD symptoms (total scores range from 0-80).
- Mean Change in PTSD Symptoms - Child PTSD Symptom Scale for DSM-5 (CPSS)Baseline (pre-treatment), Week 19 (post-treatment)
The CPSS is a child-report survey measuring the severity of PTSD symptoms in the past month. Survey items assess 20 PTSD symptoms according to DSM-5 diagnostic criteria with severity ratings for each item ranging from 0-4. Ratings for each individual symptom are summed with higher scores indicating greater severities of PTSD symptoms (total scores range from 0-80).
- Mean Change in PTSD Symptoms - Child and Adolescent Trauma Screen (CATS-2)Baseline (pre-treatment), Week 19 (post-treatment)
The CATS-2 is a caregiver-reported survey measuring the frequency of pediatric PTSD symptoms in the past four weeks. Survey items assess 20 PTSD symptoms according to DSM-5 and ICD-11 diagnostic criteria with frequency ratings for each item ranging from 0-3. Ratings for each individual item are summed with higher scores indicating greater frequencies of PTSD symptoms (total scores range from 0-60).