Improving Cholesterol Treatment for Heart Disease

This study is looking for better ways to help people with, or at high risk for, atherosclerosis (cholesterol buildup in the arteries) manage their cholesterol. It compares two approaches: a "Referral to Pharmacist-Driven Medication Management Program" where pharmacists help adjust lipid-lowering medications, and a "Best-Practice Alert" system that sends notifications to doctors through electronic health records. The study aims to enroll about 300 adults aged 18 to 95 who have established heart disease, diabetes, possible familial hypercholesterolemia, or are at high risk. Success will be measured by how many participants reach their target LDL-C (bad cholesterol) levels after 6 months. The current recruitment status is unclear.

Study design
This interventional study plans to enroll about 300 participants. It uses a systematic allocation at the provider level, meaning doctors are assigned to one of two strategies.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 6 months after notification to measure their LDL-C levels.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06960655

Improving Lipid Optimization Quality and Treatment Options in ASCVD

Enrolling by Invitation
NAAges 18–95InterventionalTreatment
Brigham and Women's Hospital
~300 participants
Updated 2026-05-18 on ClinicalTrials.gov
What's tested:Referral to Pharmacist-Driven Medication Management ProgramBest-Practice Alert

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Achieving Goal LDL-C
Measured over 6 months after notification
Hypercholesterolemia
ASCVD

NCT06960655

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Brigham and Women's Hospital

    Boston, Massachusettsno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Benjamin Scirica, M.D., MPH · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

\>18 years old and \<=95 years old
Established Atherosclerotic Cardiovascular Disease
Diabetes
Possible Familial Hypercholesterolemia (FH)
High-Risk Primary Prevention

Exclusion

No PCP, cardiologist, endocrinologist, or nephrologist at MGB
ESRD on dialysis
Enrolled in a hospice program
Advanced dementia
  • Achieving Goal LDL-C6 months after notification

    % of participants who achieve LDL-c goal (\<100 mg/dL for high-risk primary prevention, \<70 mg/dL for patients with established ASCVD)