Post-Operative Biomarker-Guided Precision Medicine For Cardiovascular Risk Reduction
This study is looking at whether a combination of two common medications, rivaroxaban (a blood thinner) and atorvastatin (a cholesterol-lowering drug), can help people who have experienced heart muscle injury (Myocardial Injury After Noncardiac Surgery, or MINS) after a major surgery. You might be able to join if you are 45 or older, recently had a major surgery, and had MINS. The main goal of this pilot study is to see how easy it is to enroll people and how well they take the medications, to help plan a larger study in the future. The study aims to enroll 50 participants. The current status of the study is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It is a pilot study designed to assess feasibility and optimize future study design, with a planned enrollment of 50 participants.
- What's involved
- If you participate, you would take rivaroxaban 2.5mg twice daily and atorvastatin 80mg daily for 6 months. The study will measure the percentage of pills taken at Month 6.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pill-taking will be measured at Month 6, which is the end of the treatment period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Post-Operative Biomarker-Guided Precision Medicine For Cardiovascular Risk Reduction
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Nathaniel R. Smilowitz, MD, MS · PRINCIPAL_INVESTIGATOR · NYU Langone Health
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Percentage of pills taken at Month 6Month 6
Treatment adherence will be assessed by pill count and patient self report.