This study is exploring a new way to help people with schizophrenia by improving how their brain cells communicate. It combines active repetitive transcranial magnetic stimulation (rTMS), which uses magnetic fields to stimulate brain cells, with cognitive training, which involves playing computer games to improve thinking skills. Researchers want to see if this combination can improve the white matter in your brain, which helps different brain areas talk to each other. They will measure changes in your brain using MRI scans. You might be able to join if you are 18-60 years old and have a schizophrenia-spectrum disorder. The study is looking for 120 participants.

Study design

This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 120 participants.

What's involved

You would receive active rTMS sessions three times per visit for up to 10 visits over about two weeks. Each rTMS session takes 3-4 minutes, with 30-minute breaks between them. You would also play cognitive computer games for 15-30 minutes per session. MRI scans will be done at the beginning, after about one week, and after about two weeks.

Compensation

Not stated in the trial record.

Follow-up

Your brain changes will be measured at baseline, after about one week, and after about two weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.