This study is looking at whether fluvoxamine (an existing medication) can help prevent delirium (a sudden change in thinking and awareness) in older patients having non-heart related surgery. You might be able to join if you are 60 or older, speak English, and are having a planned non-cardiac or non-brain surgery that requires at least a two-day hospital stay. Participants will receive either fluvoxamine or a placebo (an inactive pill) on the day of surgery and the day after. The researchers want to see if fluvoxamine can reduce inflammation and the severity of delirium. This study is laying the groundwork for a larger trial to improve public health and quality of life for those at risk of delirium after surgery. The current recruitment status is unclear.

Study design

This is an interventional study with a planned enrollment of 46 participants. It compares fluvoxamine to a placebo.

What's involved

You would take either fluvoxamine or a placebo capsule on the morning and evening of your surgery day, and again on the morning and evening of the first day after surgery.

Compensation

Not stated in the trial record.

Follow-up

The study measures average monthly participant enrollment rate at 12 months, which is the duration of the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.