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Observational Study of Cervical Radiculopathy Imaging

This study is looking at people with cervical radiculopathy, a condition where a nerve in your neck is irritated or pinched. Researchers want to see how well a special type of MRI called magnetic resonance neurography (MRN) can identify nerve problems in your neck. They will compare these MRN images with results from electrodiagnostic (EDX) studies, which measure nerve and muscle function. The goal is to understand if MRN, EDX, or a combination of both, can help predict how well people respond to different treatments. You may be able to join if you are 18-60 years old, have symptoms of one-sided cervical radiculopathy for 2 to 12 weeks, and show signs of muscle weakness. The study aims to enroll 20 participants.

Study design
This is an observational study, meaning researchers will gather information without giving you a specific treatment. It plans to include 20 participants.
What's involved
You will undergo a cervical MRI with specialized magnetic resonance neurography sequences and an electrodiagnostic assessment at the beginning of the study.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints are measured at Baseline, so no long-term follow-up is specified.

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NCT06971575

Cervical Radiculopathy Imaging Using MRN With Electrodiagnostic Correlation

Recruiting
Not specifiedAges 18–60Observational
Hospital for Special Surgery, New York
~20 participants
Updated 2026-04-27 on ClinicalTrials.gov
What's tested:Magnetic resonance neurography

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Presence of abnormalities on nerve (MRN) imaging
Measured over Baseline
+1 more outcome measured

Conditions

Cervical Radiculopathy

Explore related trials

Cervical radiculopathy

Where it's being run

1 sites across 1 states
New York1

Who to contact

J. Levi Chazen, MD
[email protected]
212-774-7149
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients presenting with symptoms compatible with acute or subacute unilateral (one-sided) cervical radiculopathy and signs of clinical weakness
18-60 years old at the time of evaluation
Symptom onset of 2 to 12 weeks leading up to baseline visit
Diagnosis of unilateral cervical radiculopathy, with or without spinal cord compression, based on signs and symptoms, physical exam and supported by MRI findings of radiculopathy (as evidenced by foraminal stenosis/narrowing) based on standard-of-care cervical spine MRI
Patients who have undergone or have planned electrodiagnostic testing at HSS prior to surgery

Exclusion

Prior cervical surgery or instrumentation
Those who have had a prior episode of cervical radiculopathy
History of peripheral neuropathy or another acute or chronic neurodegenerative condition
History of stroke, cerebellar disease, or central nervous system disease
Contraindications to undergoing a standard MRI examination (e.g., pregnancy)
Patients presenting with bilateral cervical radiculopathy

What this trial measures

  • Presence of abnormalities on nerve (MRN) imagingBaseline

    Presence of abnormalities on cervical MRN imaging that correspond to clinical findings of cervical radiculopathy. This includes abnormalities in extraforaminal cervical nerve root intraneural T2 signal and DTI values.

  • Relationship between abnormalities on imaging and electrodiagnostic assessmentBaseline

    The relationship between any abnormalities identified on nerve imaging (cervical MRN) and electrodiagnostic findings will be assessed.