Post-Stroke Aphasia TMS Study

This study is looking at how a treatment called transcranial magnetic stimulation (TMS) combined with semantic feature analysis (SFA) language therapy can help stroke survivors with aphasia (difficulty with language) improve their word-finding abilities. Participants will receive either Precision TMS with SFA, which targets a specific area of the brain, or Control TMS with SFA, which targets a different area. The study aims to enroll 50 participants who are at least 18 years old, had a left hemisphere stroke, and are fluent in English. We want to see if Precision TMS leads to greater improvements in naming accuracy. The study is currently unclear on its recruitment status.

Study design: This interventional study plans to enroll 50 participants. It compares two different approaches to TMS therapy: Precision TMS with SFA versus Control TMS with SFA.
What's involved: Participants will receive SFA+TMS treatment. Their accuracy on a picture naming test will be measured immediately after and 8-12 weeks after their last treatment.
Compensation: Not stated in the trial record.
Follow-up: Participants will be followed for 8-12 weeks after their last SFA+TMS treatment to assess their picture naming accuracy.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Post-Stroke Aphasia TMS

Recruiting

NAAges 18+InterventionalTreatment

Medical College of Wisconsin

~50 participants

Updated 2026-07-10 on ClinicalTrials.gov

What's tested:Precision TMS with SFAControl TMS with SFA

At a glance

Recruiting sites

1 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Accuracy on a picture naming test

Measured over immediately after and 8-12 weeks after last SFA+TMS treatment

Conditions

Aphasia

Stroke

Language

NCT06974279

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

Medical College of Wisconsin
Milwaukee, Wisconsinstudy coordinator listed
Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Sidney Schoenrock, MA

[email protected]

414-955-7579

Email the study team

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Eligibility criteria

Inclusion

Diagnosed with left hemisphere stroke

Consent date \>= 1 month after stroke onset

Fluent in English

18 years of age or older

Exclusion

Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing

Presence of major untreated or unstable psychiatric disease (e.g. schizophrenia, bipolar disease)

A chronic medical condition that is not treated or is unstable

The presence of cardiac stimulators or pacemakers or intracardiac lines, neurostimulators, medication infusion device, any other implants near the scalp (e.g., cochlear implants) or in the eye, metal in the body (e.g., splinters, fragments, clips)

Pregnancy

History of skull fractures, or skin diseases

History of ongoing or unmanaged seizures

Presence of factors that potentially decrease seizure thresholds: on pro-convulsant medications, untreated sleep deprivation or insomnia, ongoing alcoholism or illegal drug abuse (e.g., cocaine or MDMA users)

History of dyslexia or other developmental learning disabilities

What this trial measures

Accuracy on a picture naming testimmediately after and 8-12 weeks after last SFA+TMS treatment
Changes in accuracy on untrained stimuli after SFA+TMS compared between groups (precision, control).

Trialytics