Haystack™ ctDNA Test for Lung Cancer Treatment Guidance

This study is looking at how a blood test called the Haystack™ ctDNA Assay can help doctors decide on the best treatment after surgery for people with Stage II-III non-small cell lung cancer (NSCLC). The test looks for tiny bits of cancer DNA in your blood to see if any cancer cells might still be present after surgery. Researchers want to see if using this test to guide treatments like radiation therapy, immunotherapy, or targeted therapy can improve how well patients do. You may be able to join if you are 18-90 years old, have Stage II-III NSCLC, and have recently had surgery for your lung cancer. The study aims to enroll 25 participants, but the current recruitment status is unclear.

Study design
This is a pilot, single-arm study, meaning all participants will receive the Haystack™ ctDNA Assay. It aims to enroll 25 participants.
What's involved
You will have blood samples taken at baseline, 2-4 weeks, 3 months, 6 months, and 12 months after surgery to detect circulating tumor DNA.
Compensation
Not stated in the trial record.
Follow-up
Your circulating tumor DNA levels will be measured for up to 12 months after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06979661

Trial of ctDNA of Guidance to Determine PostOperative Radiation Therapy

Not Yet Recruiting
EARLY_PHASE1Ages 18–90InterventionalDiagnostic
Rutgers, The State University of New Jersey
~25 participants
Updated 2025-05-20 on ClinicalTrials.gov
What's tested:Haystack™ ctDNA Assay

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Detection of Circulating Tumor DNA (ctDNA) Post-Surgery
Measured over Baseline, 2-4 weeks, 3 months, 6 months, and 12 months post-surgery
Lung Cancer
Non Small Cell Lung Cancer
Lung Cancer Recurrent
1 sites across 1 states
New Jersey1

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  • Detection of Circulating Tumor DNA (ctDNA) Post-SurgeryBaseline, 2-4 weeks, 3 months, 6 months, and 12 months post-surgery

    This outcome will assess the presence or absence of circulating tumor DNA (ctDNA) in blood samples collected at multiple time points following surgical resection of Stage II-III non-small cell lung cancer (NSCLC). The Haystack™ ctDNA assay will be used to detect minimal residual disease (MRD), and results will be evaluated for their ability to predict recurrence and guide postoperative radiation and systemic therapy decisions.