Study of LPX-TI641 for Atopic Dermatitis and Psoriasis

This study is testing a drug called LPX-TI641 for people with atopic dermatitis (a type of eczema) or psoriasis. We want to see how safe LPX-TI641 is and how well your body handles it compared to a placebo (a pill that looks the same but has no medicine). You would take LPX-TI641 or the placebo by mouth once a day for 28 days. The main goal is to check for any side effects and how well you tolerate the drug. We will also look at how the drug moves through your body. This study is for adults aged 18 and older.

Study design
This is a randomized, double-blind study, meaning participants are randomly assigned to receive either LPX-TI641 or placebo, and neither you nor your doctor will know which you are receiving. Up to 48 participants with atopic dermatitis or psoriasis will be included.
What's involved
You would take LPX-TI641 or placebo by mouth once a day for 28 consecutive days. You would also need to follow study protocol requirements and restrictions.
Compensation
Not stated in the trial record.
Follow-up
Your safety and tolerability will be evaluated for 84 days after starting the medication.

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NCT06982352

Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis

Recruiting
PHASE1Ages 18+InterventionalTreatment
LAPIX Therapeutics Inc.
~48 participants
Updated 2025-12-19 on ClinicalTrials.gov
What's tested:LPX-TI641Placebo

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To evaluate the safety and tolerability after multiple oral doses of LPX-TI641 in participants with PsO and AD.
Measured over 84 days
Atopic Dermatitis (AD)
Psoriasis (PsO)
3 sites across 3 states
North Dakota1
Texas1
Jordan1

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  • To evaluate the safety and tolerability after multiple oral doses of LPX-TI641 in participants with PsO and AD.84 days

    Rate and severity of treatment-emergent adverse events, including serious adverse events.