Accelerated TMS for Freezing of Gait in Parkinson's Disease
This study is looking into a new way to help people with Parkinson's disease (PD) who experience "freezing of gait" (FOG). FOG is when you suddenly feel stuck and can't move your feet, even if you want to. The study will test a personalized brain stimulation method called repetitive transcranial magnetic stimulation (rTMS), combined with walking exercises. Researchers want to see if this treatment is safe and tolerable for people with PD and FOG, and if it shows early signs of improving walking and reducing freezing episodes. You may be able to join if you are 50-80 years old, have a PD diagnosis, and experience FOG. The study aims to enroll 12 participants.
- Study design
- This is a single-arm study, meaning all 12 participants will receive the same treatment. The phase of the study is not specified.
- What's involved
- Participants will receive personalized brain stimulation and gait training over 6 treatment days. Adherence to study visits will be tracked across the total study duration, up to 16 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Adherence to study visits will be measured across the total study duration, up to 16 weeks.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Accelerated TMS for Freezing of Gait in Parkinson's Disease
At a glance
Conditions
NCT06982638
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Medical University of South Carlina
Charleston, South Carolinastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Tolerability of the InterventionImmediately after each TMS session during the 6 treatment days
Participant-reported discomfort after each TMS session using a modified version of the Non-Invasive Brain Stimulation (NIBS) Tolerability Questionnaire, which rates six side effects (headache, pain, scalp irritation, facial twitching, fatigue, fear/anxiety) from 1 (Mild) to 10 (Severe).
- Adherence to Study VisitsAcross the total study duration, up to 16 weeks
The proportion of scheduled study visits completed by each participant, calculated as the number of attended sessions divided by the number of planned sessions.