Menstrual Cycle-Synced Neuromuscular Training for ACL Injury Prevention

This study is looking at how a special exercise program, called Menstrual Cycle-synced Neuromuscular Training Program (MC-synced NTP), can help prevent ACL (anterior cruciate ligament) injuries in young female athletes. It compares this program to a standard, or 'Blinded NTP,' to see if timing exercises with a girl's menstrual cycle makes the training more effective. You might be able to join if you are a healthy female high school athlete, aged 13-19, who plays running or pivoting sports like soccer or basketball, and has regular periods. The study aims to enroll 148 participants and will measure success by how well participants attend and engage with the program, and their feedback. The current recruitment status is unclear.

Study design
This is an interventional study comparing two different neuromuscular training programs. It plans to enroll 148 female participants.
What's involved
You would participate in an 8-week training program and complete participant feedback surveys. You would also need a mobile phone capable of syncing with a wearable device.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints are measured from the beginning to the end of the 8-week training program.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06983184

Menstrual Cycle-Synced Neuromuscular Training

Enrolling by Invitation
NAAges 13–19InterventionalPrevention
Sophia Ulman
~148 participants
Updated 2026-07-01 on ClinicalTrials.gov
What's tested:MC-synced NTPBlinded NTP

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Attendance Rate
Measured over From beginning to end of 8-week training program
+3 more outcomes measured
ACL Injuries

NCT06983184

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Scottish Rite for Children

    Frisco, Texasno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Healthy, female high school athlete who participate in running/pivoting sports (e.g., soccer and basketball)
Aged 13-19 years
Participants must also have a mobile phone, personally or via a parent, capable of downloading the Oura Ring app and of syncing to a wearable device via Bluetooth.
Participants will not be excluded from participation if they report irregular periods (not a typical 28-day cycle) or use of hormonal birth control.

Exclusion

Have been diagnosed with any musculoskeletal or neuromuscular condition that would impact their movement patterns or training performance
Report not yet starting their menses or not currently menstruating (no period in the prior 3 months).
Females in the general student body who are not an active participant of the school's soccer or basketball program will be excluded from the study.
Participants will be withdrawn if they become pregnant during the course of the study.
  • Attendance RateFrom beginning to end of 8-week training program

    Rate of attendance at training program

  • Engagement RateFrom beginning to end of 8-week training program

    Level of engagement throughout participation in training program as rated by the study team on a scale of "Very Dissatisfied" to "Very Satisfied".

  • Participant feedback surveyFrom beginning to end of 8-week training program

    Participant feedback on training program through a 3-question participant questionnaire.

  • Biomechanical risk factors associated with ACL injury during dynamic, sport-related tasksFrom beginning to end of 8-week training program

    Changes in biomechanical risk factors associated with ACL injury during dynamic, sport-related tasks as evaluated through changes in motion capture analysis of six dynamic, sport-like tasks (step down tap, drop vertical jump, single leg hop, lateral shuffle, deceleration / plant, run-cut / change-of-direction).