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Sacral Neuromodulation for Overactive Bladder

This study is looking at how different ways of setting up sacral neuromodulation (SNM) — a treatment that uses electrical pulses to help with bladder problems — can improve symptoms for people with overactive bladder (OAB). Researchers are comparing two methods: one based on visual-motor responses (VMRs) and another based on sacral evoked responses (SERs). The goal is to see which method leads to better bladder function. You might be able to join if you are an adult (18 or older) and are already eligible to receive an SNM implant for your OAB as part of your regular medical care. The study aims to enroll 15 participants, but its current recruitment status is unclear.

Study design
This interventional study plans to enroll 15 participants. It compares two different ways of setting up sacral neuromodulation (SNM) devices.
What's involved
You would receive an SNM implant and have your bladder function scored over approximately 3 months.
Compensation
Not stated in the trial record.
Follow-up
Your bladder function will be measured from the start of the study through its conclusion, which is approximately 3 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06983470

Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation

Recruiting
NAAges 18+InterventionalTreatment
University of Michigan
~15 participants
Updated 2025-12-18 on ClinicalTrials.gov
What's tested:SNM based on visual-motor responses (VMRs)SNM based on sacral evoked responses (SERs)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in bladder function score during SNM using visual-motor responses (VMR)-selected stimulation programs
Measured over Baseline through the conclusion of study participation, approximately 3 months
+1 more outcome measured

Conditions

Overactive Bladder

Explore related trials

Overactive Bladder

Where it's being run

1 sites across 1 states
Michigan1

Study leadership

  • Tim Bruns, PhD · PRINCIPAL_INVESTIGATOR · University of Michigan

Who to contact

Yike Liu
[email protected]
734-763-7104
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Determined by the research team to be fully eligible to receive a sacral neuromodulation implant at a sacral nerve as part of their normal clinical care for overactive bladder (OAB).
Adult (18 or older), capable of providing own informed consent and communicating clearly with research team.
Capable of speaking, reading, and understanding English, as all study questionnaires are standardized assessments only available in English.

Exclusion

Areflexive or atonic bladder.
Pregnant or planning to become pregnant. If a woman of child-bearing potential wishes to participate in this study, they will be pre-screened with a test to detect pregnancy.
Diagnosed neurogenic bladder, sacral nerve damage, lower motor dysfunction, or other conditions that would affect the neural circuits involved in micturition.

What this trial measures

  • Change in bladder function score during SNM using visual-motor responses (VMR)-selected stimulation programsBaseline through the conclusion of study participation, approximately 3 months

    Bladder function score is assessed using the American Urological Association Symptom Index. The American Urological Association Symptom Index has a range of 0 (no dysfunction) to 35 (maximum dysfunction). A decrease in score indicates improvement.

  • Change in bladder function score during SNM using sacral evoked responses (SER)-selected stimulation programsBaseline through the conclusion of study participation, approximately 3 months

    Bladder function score is assessed using the American Urological Association Symptom Index. The American Urological Association Symptom Index has a range of 0 (no dysfunction) to 35 (maximum dysfunction). A decrease in score indicates improvement.