This study is looking at how your kidneys respond to exercise in hot conditions and if Vitamin B3 (1000mg once a day for two days) can change that response. Researchers want to understand how chemicals in your body change under different levels of heat stress and if Vitamin B3 plays a role. You might be able to join if you are a healthy volunteer between 18 and 45 years old, a non-smoker, and physically fit. You also need to have healthy kidney function, as shown by specific blood and urine tests. The study will measure certain kidney markers (Urinary neutrophil gelatinase-associated lipocalin, Urinary TIMP2, and IGFBP7) before and right after heat exposure to see the impact. The current recruitment status is unclear.

Study design

This is an interventional study planning to enroll 28 healthy volunteers. It involves comparing chemical changes in participants under different heat stress levels and when taking either Vitamin B3 or a placebo.

What's involved

You would participate in two stages, potentially involving up to five exercise sessions on a rowing machine in a hot and humid room, each session separated by about a week.

Compensation

Not stated in the trial record.

Follow-up

Kidney markers are measured immediately after heat stress exposure, but no further follow-up is specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.