Virtual Contexts for Affective Modulation Study

This study is looking at how different virtual environments and your ability to control pain affect how you experience pain, anxiety, and your actions. Researchers will use brief heat stimuli (Pain Threat Manipulation) in virtual settings to see how feeling threatened changes your pain perception and body's responses. They will also explore how having control over pain (Pain Controllability Manipulation) impacts these feelings. The study aims to enroll 20 participants between 18 and 55 years old. You cannot have a history of depression, bipolar disorder, other psychiatric diagnoses, seizure disorder, stroke, chronic pain, or migraines. The main goals are to measure your pain intensity and anxiety levels during the study sessions, which are expected to be completed within one month.

Study design
This is an interventional study planning to enroll 20 participants. It is not specified if it is randomized, blinded, or its phase.
What's involved
You will receive brief thermal pain stimuli in virtual environments and interact with a button to potentially reduce or avoid pain. Your pain intensity and anxiety will be measured throughout testing sessions, which are expected to be completed within one month.
Compensation
Not stated in the trial record.
Follow-up
Pain intensity and anxiety ratings will be measured throughout testing sessions, on average complete within 1 month.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06986122

Virtual Contexts for Affective Modulation

Recruiting
NAAges 18–55InterventionalBasic science
Trustees of Dartmouth College
~20 participants
Updated 2025-10-31 on ClinicalTrials.gov
What's tested:Pain Threat ManipulationPain Controllability Manipulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pain Intensity Ratings
Measured over 3-10 sec post-stimulus throughout testing sessions, on average complete within 1 month
+1 more outcome measured
Pain Control
Anxiety
Memory

NCT06986122

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Dartmouth College

    Hanover, New Hampshireno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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  • Pain Intensity Ratings3-10 sec post-stimulus throughout testing sessions, on average complete within 1 month

    Self-reported pain level following each thermal stimulus, measured on a visual analog scale. 0-100 scale with 0 indicating no pain and higher values indicating more pain.

  • Self-Reported Anxiety RatingsEvery 45-60 sec throughout testing sessions, on average complete within 1 month

    Participants rate their current level of anxiety using a 0-100 visual analogue Subjective Units of Distress Scale (SUDS). 0 indicates no anxiety and higher values indicating more anxiety.