Observational Study on SIBO in Pancreatic Cancer Patients

This study aims to understand how common Small Intestinal Bacterial Overgrowth (SIBO) is in people with pancreatic adenocarcinoma (PDAC), a type of pancreatic cancer, especially those experiencing weight loss. Researchers want to see if there's a link between SIBO and weight loss, as well as if prior pancreatic surgery plays a role. You could be eligible if you are 18 or older, have a diagnosis of pancreatic adenocarcinoma, and are experiencing weight loss. The study will involve testing for SIBO using a Lactulose Hydrogen Breath Test. The main goal is to find out the prevalence of SIBO in this group of patients. This is an observational study, meaning no specific treatments are being tested, and it plans to include 100 participants.

Study design
This is an observational study that plans to enroll 100 participants. It is not testing any specific interventions or drugs.
What's involved
You would undergo a Lactulose Hydrogen Breath Test at a screening visit. The trial record does not specify additional visits or procedures.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, SIBO in PDAC, is measured at the screening visit. No further follow-up is specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06988150

Small Intestinal Bacterial Overgrowth (SIBO) in Pancreatic Adenocarcinoma (PDAC)

Recruiting
Not specifiedAges 18+Observational
Cedars-Sinai Medical Center
~100 participants
Updated 2025-05-23 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
SIBO in PDAC
Measured over At Screening Visit
Pancreatic Adenocarcinoma
Weight Loss

NCT06988150

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Cedars-Sinai Medical Center

    Los Angeles, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Andrew E. Hendifar, M.D., M.P.H. · PRINCIPAL_INVESTIGATOR · Cedars-Sinai Medical Center

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Eligibility criteria

Inclusion

Men, Women, and all genders
Individuals 18 years old or older are included.
Patients of the study investigators and team members
Diagnosis of pancreatic ductal adenocarcinoma
All subjects must consent to this study
Clinically diagnosed weight loss

Exclusion

Minors
Pregnant Women
Any records flagged "break the glass" or "research opt out."
Patients who have received treatment for SIBO in the past 3 months
  • SIBO in PDACAt Screening Visit

    Assess the prevalence of SIBO in consecutive PDAC patients with clinically significant weight loss.