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Understanding Individual Food Responses for Blood Sugar Control

This study is looking for people with prediabetes, type 2 diabetes, or healthy individuals aged 18-80 to understand why different people react differently to the same foods, especially regarding blood sugar levels after eating. You'll wear a continuous glucose monitor (CGM) and test various foods, supplements like fiber or amino acids, and short exercises to see how they affect your blood sugar. The goal is to find out if certain foods or ingredients can help manage blood sugar better for specific groups of people. To join, your BMI (body mass index) should be between 19 and 45, and your HbA1c (a measure of average blood sugar) should be 7.0% or less if you're not taking diabetes medication. The study aims to enroll 100 participants.

Study design
This is an interventional study, meaning participants will receive specific interventions. It plans to enroll 100 participants.
What's involved
You will be provided with a continuous glucose monitor (CGM) and pre-measured cooked rice to test with different mitigators like fiber, acid, amino acids, whole protein, and exercise on separate days. You may also be asked to collect blood microsamples, saliva samples, and a stool sample.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoints, post-meal peak glucose levels and glucose area under the curve, will be measured at 3 hours after eating.

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NCT06989164

Post Prandial Individual Responses to Different Foods

Recruiting
NAAges 18–80InterventionalPrevention
Stanford University
~100 participants
Updated 2025-12-02 on ClinicalTrials.gov
What's tested:Post prandial testing

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Post prandial peak glucose levels
Measured over 3 hours
+1 more outcome measured

Conditions

PreDiabetes
Diabetes Mellitus, Type 2
Healthy

Explore related trials

HealthyPrediabetesType 2 Diabetes Mellitus

Where it's being run

1 sites across 1 states
California1

Who to contact

Sabrina Chun Johnston, MS, RD
[email protected]
(650) 725-0169
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

BMI (body mass index) \>19 kg/m2 but \< 45 kg/m2
HbA1c \< or equal to 7.0% while not on antihyperglycemic medications
Be willing to provide written informed consent for all study procedures.
Able to commute to Stanford campus for on-site visits

Exclusion

recent (\<6mos) CVD (cardiovascular disease) event
active malignancy
kidney/liver disease
pregnancy/lactation
chronic inflammatory disease
eating disorder
bariatric surgery
history of acute pancreatitis
current use of antihyperglycemic, diabetogenic, or weight loss medications
heavy alcohol use
physical activity \>2 hours/day
inability to come to Stanford CTRU (Clinical and Translational Research Unit) for metabolic testing

What this trial measures

  • Post prandial peak glucose levels3 hours

    Delta glucose peak within 3 hours after consuming the standard meal - peak glucose value minus baseline glucose value at time 0 measured by CGM in mg/dL.

  • Post prandial glucose area under the curve (AUC)3 hours

    AUC (\>baseline) within three hours measured by CGM in mg/dL during the 3 hours after each study meal.