This study is looking at a new training method called "MEP Up-conditioning" for people with chronic spinal cord injury (SCI) that affects their neck (cervical SCI). The training involves non-invasive brain stimulation and feedback to help strengthen the connection between the brain, spinal cord, and wrist extensor muscles. Researchers want to see if this training can improve how well you can move your arm and hand. They will also use brain and spine MRI scans before and after the training to understand how spinal damage and brain function relate to movement and how people respond to the training. You might be able to join if you are an adult, had a spinal cord injury at or above C6 more than 6 months ago, and have some weakness in your wrist extension.

Study design

This is an interventional study with a planned enrollment of 11 participants. The study is not specified as randomized, blinded, or a particular phase.

What's involved

You would participate in a 10-week training protocol. This includes sessions where electrodes are placed on your arm to measure muscle responses and you receive non-invasive brain stimulation. Brain and spine MRI scans will be collected before and after the training.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint measures are taken as an average of the last 6 conditioning sessions (over weeks 8-10), indicating follow-up throughout the 10-week training period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.