Study of Partner-Assisted Prolonged Exposure for PTSD in Veterans
This study is comparing two types of therapy for Post-Traumatic Stress Disorder (PTSD) in post-9/11 Veterans. One therapy is called Partnered Prolonged Exposure (PPE), which involves both the Veteran and their partner in some sessions. The other is standard Prolonged Exposure (PE) therapy, which is for the Veteran only. The study aims to see if involving a partner can improve treatment results, especially for overall well-being and daily functioning. Researchers will measure changes in your psychosocial functioning using a tool called the Inventory of Psychosocial Functioning (IPF) at several points during and after treatment. You may be eligible if you are a post-9/11 Veteran with a PTSD diagnosis, are in a committed relationship, and meet other health criteria. The study plans to enroll 420 participants, but its current recruitment status is unclear.
- Study design
- This is an interventional study comparing two behavioral therapies, Partnered Prolonged Exposure (PPE) and Prolonged Exposure (PE), with a planned enrollment of 420 participants.
- What's involved
- If you participate, you would attend therapy sessions, either twice-weekly 60-minute sessions (PPE) or weekly 90-minute sessions with a 30-minute check-in (PE). Your psychosocial functioning will be measured at baseline, mid-treatment, immediately after treatment, and then 3 and 6 months later.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 6 months after treatment ends to assess their psychosocial functioning.
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A Hybrid 1 Effectiveness-Implementation Trial of Partner-Assisted Prolonged Exposure for PTSD
At a glance
Conditions
Where it's being run
4 sites across 4 statesStudy leadership
- Laura Meis, PhD · PRINCIPAL_INVESTIGATOR · University of Minnesota, National Center for PTSD, Minneapolis VA Healthcare System
- Leslie Morland, PhD · PRINCIPAL_INVESTIGATOR · National Center for PTSD; San Diego VA Healthcare System
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Inventory of Psychosocial Functioning (IPF)Baseline, mid-treatment (between session 5-6), posttreatment (immediately after treatment closes), and 3-months and 6-months after treatment closes.
The primary outcome is Veterans' global functioning at posttreatment assessment. The subdimensions of global functioning that matter most to Veterans with PTSD are their relationships with intimate partners, family relationships, work performance, friend relationships, parenting, educational performance, and self-care functioning (e.g., maintaining personal hygiene, exercising, household chores, healthy eating). Outcomes will be measured using the Inventory of Psychosocial Functioning (IPF).