CLOSM Trial: Groin Closure Using Layered Option for Suture Material

This study, called the CLOSM trial, is looking at the best way to close groin incisions (cuts) after vascular surgery. Researchers are comparing two different types of stitches: PDS (polydioxanone) suture and Vicryl suture. The goal is to see which type of stitch leads to fewer complications in the groin area. You might be able to join if you are over 18 and having planned (elective) vascular surgery that requires a groin incision. If you have incisions on both sides, one side might get PDS and the other Vicryl. The main thing they'll be looking at is the rate of groin complications after 30 days and after 1 year. The current status of this study is unclear, but it plans to enroll 259 participants.

Study design
This is a randomized controlled trial comparing two types of sutures. About 259 participants will be randomly assigned to receive either PDS or Vicryl suture for their groin closure.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed to check for groin complications at 30 days and 1 year after surgery.

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NCT06990425

CLOSM Trial: Groin Closure Using Layered Option for Suture Material

Recruiting
NAAges 18+InterventionalTreatment
The Cleveland Clinic
~259 participants
Updated 2026-06-03 on ClinicalTrials.gov
What's tested:Groin closure with PDS sutureGroin closure suture material

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rate of groin complication
Measured over 30 days and 1 year
Vascular Diseases
1 sites across 1 states
Ohio1
  • Francis Caputo, MD · PRINCIPAL_INVESTIGATOR · The Cleveland Clinic

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Eligibility criteria

Inclusion

All patients \> 18 years who undergo ELECTIVE vascular surgery that would require groin incisions
Patients with to undergo ELECTIVE bilateral groin incisions will be matched to receive closure with PDS in one groin and Vicryl in the other groin
  • Rate of groin complication30 days and 1 year

    Number of occurrence of the access site complication