JX10 for Acute Ischemic Stroke

This study is testing a drug called JX10 against a placebo (an inactive substance) in people who have had an acute ischemic stroke (a stroke caused by a blood clot). The main goal is to see if JX10 can improve how well people recover and reduce their symptoms 90 days after their stroke. Researchers will also be carefully watching for any serious side effects, specifically bleeding in the brain, within 36 hours of treatment. You might be able to join if you are between 18 and 90 years old, have had a recent ischemic stroke, and meet other specific medical criteria. The study aims to enroll 740 participants.

Study design
This is an interventional study comparing JX10 to a placebo. Participants will be randomly assigned to receive either JX10 or placebo.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants' functional outcomes will be measured at 90 days after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06990867

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

Recruiting
PHASE2Ages 18–90InterventionalTreatment
Corxel Pharmaceuticals
~740 participants
Updated 2026-03-13 on ClinicalTrials.gov
What's tested:JX10Placebo

At a glance

Recruiting sites
83 of 83 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Efficacy: Proportion of participants with no or minimal symptoms (mRS score 0-1) at 90 days
Measured over 90 days
+1 more outcome measured
Acute Ischemic Stroke

NCT06990867

Where you'd take part

This study runs at 83 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Corxel Investigational site

    Lille, Francestudy coordinator listed

    Recruiting

  • Corxel Investigational site

    Paris, Francestudy coordinator listed

    Recruiting

  • Corxel Investigational site

    Ibaraki, Japanstudy coordinator listed

    Recruiting

  • Corxel Investigational site

    Toyota, Japanstudy coordinator listed

    Recruiting

  • Corxel Investigational Site

    Long Beach, Californiastudy coordinator listed

    Recruiting

  • Corxel Investigational Site

    Sacramento, Californiastudy coordinator listed

    Recruiting

  • Corxel Investigational Site

    Colorado Springs, Coloradostudy coordinator listed

    Recruiting

  • Corxel Investigational Site

    Washington D.C., District of Columbiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Senior Director, Clinical Operations · STUDY_DIRECTOR · Corxel Pharmaceuticals
Corxel Pharmaceuticals Study Information Center
Email the study team

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  • Efficacy: Proportion of participants with no or minimal symptoms (mRS score 0-1) at 90 days90 days
  • Safety: Incidence of symptomatic intracranial hemorrhage within 36 hours post-randomizationWithin 36 hours post-randomization