NCT06992258

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

Recruiting
PHASE2Ages 18+InterventionalTreatment
Criterium, Inc.
~120 participants
Updated 2026-03-17 on ClinicalTrials.gov
What's tested:Fruquintinib+ Lonsurf (trifluridine and tipiracil)Fruquintinib

At a glance

Recruiting sites
9 of 9 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To estimate the progression-free survival (PFS) benefit of fruquintinib in combination with TAS-102 as compared to fruquintinib
Measured over 24 months
Colorectal Cancer
9 sites across 8 states
Florida2
Connecticut1
New Jersey1
New York1
Pennsylvania1
Tennessee1
Texas1
Virginia1

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  • To estimate the progression-free survival (PFS) benefit of fruquintinib in combination with TAS-102 as compared to fruquintinib24 months

    Progression free survival (PFS) defined as time from randomization to first observation of progression using RECIST v1.1 or death from any cause.