This study is looking at how the stiffness of your cornea (the clear front part of your eye) changes in people with glaucoma. Researchers will use a special non-contact imaging device called Brillouin microscopy to measure corneal stiffness. They want to see if these measurements can help understand glaucoma risk and how it progresses. You might be eligible if you are 18 or older, have primary open angle glaucoma (POAG) or no history of glaucoma, and have not used glaucoma eye drops before. The study will observe changes in corneal stiffness over 6 weeks in people who are prescribed prostaglandin analogue-containing IOP-lowering therapy or beta blockers for their glaucoma. The goal is to see if these measurements can be used as indicators for glaucoma.

Study design

This is an observational study with a planned enrollment of 60 participants. It will compare corneal stiffness between different groups and observe changes over time.

What's involved

You would have your corneal biomechanics measured at the start, at 3 weeks, and at 6 weeks. You would also be observed if you are prescribed prostaglandin analogue-containing IOP-lowering therapy or beta blockers.

Compensation

Not stated in the trial record.

Follow-up

Your corneal biomechanics will be measured at baseline, 3 weeks, and 6 weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.