Plant-Based Diet for Coronary Artery Disease
This study is looking at how a specific plant-based diet affects people with coronary artery disease (CAD), a condition where blood vessels supplying the heart become narrowed. The study will involve 30 participants who will follow a defined plant-based diet for 42 days. Researchers will measure changes in your blood vessel function (endothelial function) at the beginning and after 4 weeks to see if the diet helps. You may be able to join if you are between 18 and 75 years old, have CAD, and are a new patient at the clinic. You cannot participate if you currently use tobacco, drink excessive alcohol, have cancer, an active infection, severe kidney disease (eGFR < 30), are pregnant or breastfeeding, or have been hospitalized in the last 6 months.
- Study design
- This is an interventional study planning to enroll 30 participants. It will compare a plant-based diet with standard medical care.
- What's involved
- You will follow a defined plant-based diet for 42 days. All food will be provided to you.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your blood vessel function will be measured at enrollment and again at week 4.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Clinical and Biochemical Effects of a Defined Plant-Based Diet on Heart Disease
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Improved endothelial function via reactive hyperemia index (RHI)enrollment and at week 4
Peripheral microvascular function will be measured by PAT plethysmographic device (EndoPAT, Itamar®). The device consists of a finger probe with a transducer to assess digital volume changes accompanying pulse-waves. An inflatable cuff is placed on one arm (test arm), while amplitudes are recorded from the test arm and the contralateral control arm. Reactive hyperemia index (RHI) is obtained by the following: 5 minutes of baseline amplitude signal detection, 5 minutes of arterial occlusion by suprasystolic cuff inflation, and then 6 min of post-occlusion amplitude signal detection. RHI is a unit-less measure calculated as a ratio of hyperemic to baseline flow signal. It takes into account the baseline signal and adjusts it to the changes in the contralateral arm