Digital Interventions for Alcohol and Atrial Fibrillation Severity
This study is looking at how digital messages can help people with atrial fibrillation (AF), a common heart rhythm problem, manage their alcohol intake. You could join if you are 21 or older, have AF, use a smartphone, and drink alcohol at least once a month. The study compares two approaches: one group gets messages encouraging them to follow current guidelines for moderate drinking, while the other group gets messages encouraging them to avoid all alcohol. Researchers will track changes in your AF severity over one year to see which approach is more effective. The study is currently unclear on its recruitment status.
- Study design
- This is a single-center, randomized, controlled study with a planned enrollment of 1000 participants. Participants will be randomly assigned to one of two digital health interventions.
- What's involved
- You will receive weekly app and text-based messages for one year. Your alcohol consumption and AF episodes will be assessed through regular surveys.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your atrial fibrillation severity will be measured from the start of the study to one year of participation.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Digitally Rendered Interventions And Knowledge To Limit Ethanol-Associated Atrial Fibrillation Severity
At a glance
Conditions
NCT06995391
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
UCSF Medical Center at Parnassus
San Francisco, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Gregory M Marcus, MD, MAS · PRINCIPAL_INVESTIGATOR · University of California, San Francisco
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Want this trial checked against your situation?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Change in atrial fibrillation severity at one yearFrom baseline to one year of study participation.
The primary outcome will be change in atrial fibrillation severity at one year, defined by a change in the Atrial Fibrillation Effect on Quality-of-Life Questionnaire (AFEQT) score from baseline to one year associated with alcohol abstinence. Based on previously reported values of clinically relevant change in AFEQT score (PMID 31092022), the investigators estimate the change in mean AFEQT score from baseline to 1 year to be 5.4±17.03 in the Alcohol Abstinence group and 0.2±15.17 in the Contemporary Guideline-Adherence group, giving a 5.2 difference between the two groups. The investigators estimate that 1,000 patients would provide \~99% power to detect this difference with as much as 30% overall attrition, and 30% crossover from abstinence to drinking regularly and 20% crossover from drinking regularly to abstinence.