Imaging Study for Parkinson's Disease DBS
This study is looking at how a specific type of deep brain stimulation (DBS) affects the brain in people with Parkinson's disease. Researchers will use bipolar DBS stimulation through contacts 3 and 2 of the Medtronic Percept/Percept RC DBS System. The goal is to see how this stimulation changes the blood oxygen-level dependent (BOLD) signal in the leg region of the primary motor cortex, which is a part of your brain that controls movement. This change will be measured 8 hours after stimulation. You may be able to join if you are 21 or older, have Parkinson's disease, have an MR-compatible DBS device (Medtronic Percept/Percept RC DBS System), and can speak English. The study aims to enroll 20 participants.
- Study design
- This is an interventional study planning to enroll 20 participants. All participants will receive bipolar DBS stimulation.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured at 8 hours.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Imaging Core Aim 2, and Udall Project 2 Aim 2
At a glance
Conditions
NCT06998303
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
University of Minnesota
Minneapolis, Minnesotastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Noam Harel, PhD · PRINCIPAL_INVESTIGATOR · University of Minnesota
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
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Inclusion
Exclusion
What this trial measures
- Change in Blood Oxygen-Level Dependent (BOLD) signal in leg region of primary motor cortex8 hours
Data will be obtained from functional MRI scanning with the participant at rest, with DBS cycling between ON and OFF stimulation. The change in BOLD signal in the leg region of the primary motor cortex will be obtained by contrasting signals obtained during ON vs. OFF stimulation states. The change in BOLD signal represents the increase/decrease in brain activity in the leg region related to stimulation.