Observational Study of Live Tumor Fragments from Cancer Surgery

This observational study is looking at tumor tissue removed during cancer surgery. Researchers want to understand how these tumor fragments respond to treatments outside the body and how the tumor's environment (microenvironment) stays stable. They will use advanced techniques like 'omics analysis' (studying genes, proteins, etc.) and imaging. You can join if you are 18 or older, understand and sign the consent form, and are planning to have surgery to remove cancer. The study will look at how the tissue responds to treatment for up to 72 hours. The current status of this study is unclear, and it aims to enroll 250 participants.

Study design
This is an observational study planning to enroll 250 participants. It does not involve any intervention or treatment given to you.
What's involved
You would provide unused tumor tissue from your surgery and associated clinical data. There are no additional procedures or visits beyond your planned surgery.
Compensation
Not stated in the trial record.
Follow-up
The study will observe tissue response to treatment for up to 72 hours after the tissue is collected.

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NCT07000864

A Study of Live Tumor Fragments of Surgical Resections

Recruiting
Not specifiedAges 18+Observational
Mayo Clinic
~250 participants
Updated 2026-05-22 on ClinicalTrials.gov
What's tested:No intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Tissue response to treatment
Measured over Up to 72 hours
Cancer
Tumor
1 sites across 1 states
Florida1
  • Debabrata Mukhopadhyay, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

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Eligibility criteria

Inclusion

Ability to understand and sign informed consent
Planning to undergo a surgical procedure to remove cancer
No tissue for research available at time of surgery
  • Tissue response to treatmentUp to 72 hours

    Tumor sample fragments will be treated with various combination of chemotherapy and immunotherapy drugs that are commonly used to treat patients clinically (panel of drugs will be selected based on cancer type). response to the treatment will be assessed at multiple timepoints during a 72-hour period.