BrECADD Therapy for Stage 2 B-IV Hodgkin Lymphoma

This study is looking at a treatment called BrECADD for people with Stage 2 B-IV Hodgkin Lymphoma (a type of cancer that affects the lymphatic system). The BrECADD treatment involves five different medications: Brentuximab Vedotin, Etoposide, Cyclophosphamide, Doxorubicin, and Dacarbazine, given intravenously (into a vein) over four cycles. The main goal is to see how well this treatment works to prevent the cancer from growing or coming back. Researchers also want to explore if a blood test for circulating tumor DNA (ctDNA) can help understand how well the treatment is working. You may be able to join if you are between 18 and 60 years old and have been diagnosed with classical Hodgkin Lymphoma. The current status of this study is unclear.

Study design
This is an interventional study planning to enroll 48 participants. The phase of the study is not specified.
What's involved
Participants will receive intravenous medications on specific days over a 21-day cycle, for up to 4 cycles.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for progression-free survival for up to 12 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07002216

BrECADD Therapy in Stage 2 B-IV Hodgkin Lymphoma

Recruiting
PHASE2Ages 18–60InterventionalTreatment
University of Miami
~48 participants
Updated 2025-11-03 on ClinicalTrials.gov
What's tested:Brentuximab VedotinEtoposideCyclophosphamideDoxorubicinDacarbazineDexamethasone

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Progression-free survival (PFS)
Measured over Up to 12 months
Hodgkin Lymphoma
Advanced Hodgkin Lymphoma

NCT07002216

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Miami

    Miami, Floridastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Michele Stanchina, DO · PRINCIPAL_INVESTIGATOR · University of Miami

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  • Progression-free survival (PFS)Up to 12 months

    Progression-free survival (PFS) is defined as the elapsed time in months from the start of treatment until disease progression or death, whichever is earlier. Follow-up times for participants who remain alive without progression will be censored at the last documented disease assessment date.