Back to search results

Ischemic Preconditioning for Osteoarthritis and Back Pain

This study is looking at a treatment called Ischemic Preconditioning for people with knee osteoarthritis and low back pain. This treatment involves temporarily restricting blood flow to one thigh for 50 minutes, in cycles of 5 minutes on and 5 minutes off, every other day for two weeks. Researchers want to see if this helps improve your walking speed, muscle strength, and how you feel about your pain and function (Patient Reported Outcomes). You might be able to join if you are 50 years or older, have knee pain and back pain, and can walk for at least 3 minutes without help. The study is currently unclear about its recruitment status and plans to enroll 24 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 24 participants.
What's involved
You would receive the Ischemic Preconditioning or a sham intervention every other day for two weeks. Your walking speed, muscle strength, and patient-reported outcomes will be measured at the beginning and end of the intervention.
Compensation
Not stated in the trial record.
Follow-up
Your progress will be tracked from the start of the study until the end of the 3-week intervention period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07003113

Ischemic Preconditioning in Osteoarthritis and Back Pain

Recruiting
NAAges 50+InterventionalTreatment
University of Illinois at Chicago
~24 participants
Updated 2025-11-17 on ClinicalTrials.gov
What's tested:Ischemic PreconditioningSham Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Preferred walking speed
Measured over At baseline (from enrollment) until end of intervention (3 weeks).
+4 more outcomes measured

Conditions

Low Back Pain
Knee Osteoarthritis

Explore related trials

Lower Back PainOsteoarthritis of knee

Where it's being run

1 sites across 1 states
Illinois1

Study leadership

  • Lindsay Hannigan · PRINCIPAL_INVESTIGATOR · University of Illinois at Chicago

Who to contact

Shraddha Sudhir
[email protected]
312-413-5118
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Reported Knee Pain using ACR Criteria
Reported Back Pain using ODI Criteria \> 12
Ability to walk for at least 3 minutes without the use of aids
Ability to provide written informed consent

Exclusion

Younger than 50 years old
History of Knee or Hip Replacements
History of steroid injection within the previous 6 months
Presence of neuromuscular joint condition that affects lower extremity function
History of blood clots in the leg or any condition in which compression of the thigh is contraindicated
History of heart failure or thrombosis
Allergic to ultrasound gel
History of spine surgery
Non-English speaker
Currently pregnant or intends to become pregnant during the study

What this trial measures

  • Preferred walking speedAt baseline (from enrollment) until end of intervention (3 weeks).

    Changes in preferred walking speed (m/s) from intervention

  • Muscle strengthFrom baseline (enrollment) until end of intervention (3 weeks)

    Change in quadriceps, hamstring, and hip strength

  • Patient Reported OutcomesAt baseline (enrollment) through the intervention (3 weeks)

    Change in subjective function and reporting based on questionnaires

  • Gait KinematicsAt baseline (from enrollment) until end of intervention (3 weeks).

    Changes in gait kinematics (in degrees) from intervention

  • Gait Kinetics/MomentsAt baseline (from enrollment) until end of intervention (3 weeks).

    Changes in gait kinetics (joint moments) (in N/m) from intervention