Comparing Single-Session Therapies for Chronic Pain

This study is comparing three different single-session behavioral therapies for chronic musculoskeletal pain: Cognitive Behavioral Therapy (CBT), Pain Reprocessing Therapy (PRT), and Emotion Awareness and Expression Therapy (EAET). Researchers want to see if these therapies can help reduce your pain and how much it interferes with your daily life. You might be able to join if you are at least 18 years old, live in the United States, have had chronic pain for at least three months, and your pain intensity and interference are at a certain level. The study is currently unclear about its recruitment status and plans to enroll 160 participants. Success will be measured by changes in your pain severity and how much pain interferes with your life, as reported by you.

Study design
This interventional study plans to enroll 160 participants. Participants will be randomly assigned to receive one of the three therapies or a no-treatment control condition.
What's involved
You would need to attend one 90-minute session. You will also need a personal computer/tablet and internet access.
Compensation
Not stated in the trial record.
Follow-up
Your pain levels will be checked at baseline, one week after treatment, and one month after treatment.

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NCT07008105

Comparing Single-Session Therapies for Chronic Pain

Recruiting
NAAges 18+InterventionalTreatment
Mark A. Lumley
~160 participants
Updated 2025-07-15 on ClinicalTrials.gov
What's tested:Cognitive Behavioral TherapyPain Reprocessing TherapyEmotion Awareness and Expression Therapy

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Brief Pain Inventory (BPI) - Pain Severity
Measured over Baseline to 1-week post-treatment and 1-month follow-up
+3 more outcomes measured
Chronic Musculoskeletal Pain
2 sites across 2 states
Illinois1
Michigan1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Pain for at least 3 months and experienced 4 or more days/week for the past 6 months
Pain intensity last week is \>= 3 (0 to 10 rating scale)
Pain interference last week is \>= 3 (0 to 10 rating scale)
At least age 18
Lives in United States
Fluent in English
Has personal computer/tablet and internet access
Able to attend one 90-minute session
Willing to be randomized
Seeking to improve their pain-related status via a psychological therapy

Exclusion

Past 2 years (treated for or having experienced):
Complex regional pain syndrome
Epilepsy/seizure disorder
Autoimmune disease
Liver disease
Cancer
Heart disease
Substance dependence or use disorder
Schizophrenia or other psychotic disorder
Bipolar disorder
Obsessive-compulsive disorder
Borderline personality disorder
Suicide attempt or suicide intention or impulse
Major medical procedure scheduled within next 2 months
Applied for/ litigating for pain-related disability/worker's compensation (past year).
Major life event/stressor in past 6 months
Cognitive impairment (screener score \<=4)
  • Brief Pain Inventory (BPI) - Pain SeverityBaseline to 1-week post-treatment and 1-month follow-up

    4-item measure of pain severity over past week (range 0 to 10; higher scores = worse pain severity)

  • Patient-Reported Outcome Measurement Information System (PROMIS) - Pain Interference - Short Form 8aBaseline to 1-week post-treatment and 1-month follow-up

    8-item measure of pain interference over past week (range1 to 5; higher scores = more pain interference)

  • Pain Rating QuestionImmediately pre and immediately post-treatment

    1-item pain rating developed by research team asking "Please rate your pain by circling the one number that tells how much pain you have right now". (0 = No pain, 10 = Pain as bad as you can imagine; higher = more pain)

  • Symptom Rating QuestionImmediately pre and immediately post-treatment

    1 -item symptom rating developed by research team asking "Please rate your physical symptoms by circling the one number that tells how much physical symptoms you have right now". (0 = no symptoms; 10 = symptoms as bad as you can imagine; higher = more symptoms).