This study is looking into whether hydrogen water, an over-the-counter (OTC) supplement, can help adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) feel less tired and function better. Researchers also want to see if heart rate variability (HRV), which measures changes in the time between your heartbeats, can predict who will benefit most from the hydrogen water. The study aims to enroll 50 participants and will measure fatigue using the Fatigue Severity Scale after 12 months. To join, you must be between 18 and 65 years old, meet specific criteria for ME/CFS, and not have other medical conditions that explain your fatigue or any psychosis. The current status of this study is unclear.

Study design

This is an interventional study planning to enroll 50 participants. It will involve a graduated dosing schedule of hydrogen water over 16 weeks.

What's involved

Participants will follow a 10-day graduated dosing schedule, followed by a standard daily dose of hydrogen water for 16 weeks. Heart rate variability will be measured.

Compensation

Not stated in the trial record.

Follow-up

Fatigue will be measured at 12 months, suggesting a follow-up period after the 16-week intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.