Improving Hand Dexterity in Older Adults

This study is looking at ways to improve hand dexterity in older adults, specifically those aged 54 to 89. It explores how practice and a treatment called Transcutaneous Electrical Nerve Stimulation (TENS) can change the way your brain controls hand muscles. TENS uses a mild electrical current on the skin. You would practice a task to improve hand dexterity, either with TENS or a sham (inactive) TENS. Researchers will measure your hand steadiness and how your motor units (nerve and muscle fibers working together) respond. The goal is to find non-invasive ways to help older adults maintain independence and quality of life. The study plans to enroll 72 participants.

Study design
This interventional study plans to enroll 72 participants. You would either receive Transcutaneous Electrical Nerve Stimulation (TENS) or a sham (inactive) TENS while practicing a hand dexterity task.
What's involved
You would perform 25 trials of the Grooved Pegboard Test. Your force steadiness and motor unit modes would be measured from enrollment until the end of the study at 2 weeks.
Compensation
Not stated in the trial record.
Follow-up
Measurements will be taken from enrollment until the end of the study at 2 weeks.

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NCT07011160

Neural Substrates Underlying Adaptations in Manual Dexterity of Older Adults

Not Yet Recruiting
NAAges 54–89InterventionalBasic science
University of Colorado, Boulder
~72 participants
Updated 2025-06-08 on ClinicalTrials.gov
What's tested:Transcutaneous electrical nerve stimulation (TENS)Familiarization

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Grooved Pegboard Test
Measured over From enrollment until the end of the study at 2 weeks.
+2 more outcomes measured
Aging Hands
1 sites across 1 states
Colorado1
  • Roger M Enoka, PhD · PRINCIPAL_INVESTIGATOR · University of Colorado, Boulder

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  • Grooved Pegboard TestFrom enrollment until the end of the study at 2 weeks.

    Time taken to insert 25 keyhole-shaped pegs into matching holes on the pegboard.

  • Force steadinessFrom enrollment until the end of the study at 2 weeks.

    Coefficient of variation for force during low-intensity isometric contractions.

  • Motor unit modesFrom enrollment until study completion at 2 weeks.

    The subsets of motor units in hand-forearm muscles that exhibit correlated modulation of discharge rate during low-intensity isometric contractions. The motor unit activity will be identified from high-density surface electromyography with grid electrodes.