Study for Personalized Opioid Use Disorder Treatment
This study is looking for 75 adults aged 18 or older who have been diagnosed with opioid use disorder (OUD) and are receiving care at a Discovery Behavioral Health site. It aims to find the best ways to personalize treatment for OUD using a combination of medication and psychotherapy. Researchers will use information from patients to figure out which treatment plans work best to reduce the risk of overdose and improve recovery. The study will measure how well these personalized plans work by looking at changes in OUD severity, how long people stay in treatment, and how satisfied patients and clinicians are, all measured at 4 weeks. The study is currently unclear on its recruitment status.
- Study design
- This interventional study plans to enroll 75 participants. It uses a special design called a 2x2 factorial SMART design to test different combinations of medication and psychotherapy.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The main outcomes of the study are measured at 4 weeks after treatment begins.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Dynamic Treatment Regimes for Opioid Use Disorder
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- CAT-SUD severity scores4 weeks
Weekly Computerized Adaptive Test for Substance Use Disorder severity T-score. Scores range 0-100 (≈5-point precision). Higher scores indicate a greater SUD symptom burden/risk, while lower scores indicate fewer symptoms/lower risk. Prior validation studies have used \<50 = low, 50-70 = intermediate, \>70 = high severity/risk thresholds. Computerized Adaptive Test for Substance Use Disorder provides a dimensional severity score (not a diagnosis). Change is assessed week-to-week.
- Retention in treatment4 weeks
Whether participants remained engaged in behavioral health treatment through the end of the 4-week study period.
- Patient and clinician satisfaction4 weeks
Participant- and provider-reported satisfaction with the trial experience and procedures, assessed via standardized surveys.
- Clinical fidelity to intervention protocoWeekly over 4-week study period
Fidelity of intervention delivery assessed via clinician checklists or independent fidelity ratings, evaluating adherence to protocol for each assigned treatment component.
- Data completeness and consistencyThroughout the 4-week trial
Proportion of participants for whom ethical standards are fully maintained (e.g., informed consent obtained, no reported violations). Proportion of participants for whom ethical standards are fully maintained (e.g., informed consent obtained, no reported violations). Proportion of EHR and survey data points with missing or inconsistent entries. Thresholds for success include \<5% missingness or inconsistency.
- Timeliness of EHR data entryWeekly throughout the 4-week trial
Proportion of EHR entries recorded within 48 hours of patient interaction.