Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD)
This study, PRECISE-TCD, is looking at how a non-invasive test called Transcranial Doppler (TCD) can help doctors understand why some patients get worse after a procedure called endovascular thrombectomy (EVT) for a severe type of stroke. EVT is a treatment to remove blood clots in the brain. Researchers will use TCD to measure blood flow in the brain for 72 hours after EVT. The main goal is to see if these TCD measurements are linked to patients getting worse neurologically within 72 hours of their EVT. You might be able to join if you are 18 or older, have had a specific type of stroke treated with EVT, and can have a clear TCD measurement. The study status is currently unclear.
- Study design
- This is an observational study, meaning participants will be monitored without receiving a new treatment. It plans to enroll 100 participants at a single center.
- What's involved
- You would have serial TCD monitoring as soon as possible after EVT, daily for 72 hours, and potentially if your neurological condition changes or you have a head CT.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome is measured within 72 hours after EVT.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD)
At a glance
Conditions
NCT07013396
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Virginia Commonwealth University
Richmond, Virginiastudy coordinator listed
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Aarti Sarwal · PRINCIPAL_INVESTIGATOR · Virginia Commonwealth University
Who to contact
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Inclusion
Exclusion
What this trial measures
- Occurrence of early neurological deterioration (END) within 72 hours after EVTWithin 72 hours after EVT
Early neurological deterioration (END) will be assessed as a binary Yes/No outcome. A participant will be classified as having END if any of the following occurs within 72 hours after endovascular thrombectomy (EVT): an increase in total NIHSS score of ≥4 points; an increase in NIHSS item 1a score of ≥1 point; intracranial hemorrhage on CT or MRI classified using the Heidelberg Classification; or any neurological examination change prompting emergent head CT at clinician discretion. The outcome will be reported as the percentage of participants who meet the criteria for END.