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Reactions to Distress (RED) Study in Louisville, KY

This study, called Reactions to Distress (RED), is looking at how stress related to race might affect how people pay attention, and if mindfulness can help. You could be eligible if you identify as Black or African American and have experienced or witnessed racism. Participants will either get a stress condition related to race or not, and then listen to either a guided mindfulness practice or a neutral audio file. The researchers want to see if these interventions change how you look at things (free viewing task) and your feelings (affect). The study aims to enroll 270 people.

Study design
This is an interventional study that plans to enroll 270 participants. You will be randomly assigned to one of four groups.
What's involved
You will complete a 1. (The full duration of participation is not specified in the trial record.)
Compensation
Not stated in the trial record.
Follow-up
Your attention will be measured at 10 minutes and your affect (feelings) at 5 minutes after the intervention.

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NCT07016945

Reactions to Distress (RED) In Louisville, KY Study

Recruiting
NAAges 18+InterventionalBasic science
University of Louisville
~270 participants
Updated 2025-06-12 on ClinicalTrials.gov
What's tested:Stress and Mindfulness Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Free viewing task
Measured over 10 minutes
+1 more outcome measured

Conditions

Threat Sensitivity

Explore related trials

Stress

Where it's being run

1 sites across 1 states
Kentucky1

Who to contact

Yara Mekawi, PhD
[email protected]
16308636375
Email the study team

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Eligibility criteria

Inclusion

Eligibility for this study will include a positive response to the following questions: 1) Do you identify as Black or African American? 2) Have you ever in your lifetime personally experienced or witnessed another person experience any acts of racism or racial microaggressions? 3) Are you willing to complete a 1.5-hour study at the University of Louisville in the next 2 weeks? 4) Are you 18 or older?

Exclusion

None

What this trial measures

  • Free viewing task10 minutes

    Free Viewing Task. This is the outcome measure for both manipulations listed above. To assess attention bias to threat, we will use a free-viewing task in which participants are instructed to freely view a pair of images side by side across two blocks of 60 trials each. In Block 1, participants will view two types of image pairs: one threatening (i.e., angry face) and one neutral (i.e., neutral facial expression) or both neutral.

  • Affect5 minutes

    To ensure that the manipulations outlined above are having the intended effect (increase in NA/ decrease in PA after stress manipulation and the opposite after the mindfulness manipulation), participants will complete the 20-item PANAS after each manipulation. The items ask participants to indicate how they are feeling in the moment in terms of both negative affect (e.g., distressed, interested) and positive affect (e.g., strong, inspired) on a scale of 1 (very slightly or not at all) to 5 (very much). Scores are summed to create a total negative affect and positive affect score.