Ovarian PRP Injections for Improved Embryo Quality

This study is looking at whether ovarian platelet-rich plasma (PRP) injections can improve the quality of embryos for women experiencing infertility, poor ovarian reserve, or embryo growth disorders. PRP is a treatment where your own blood is processed to concentrate platelets, which are then injected into your ovaries. Researchers will compare embryo development before and after PRP treatment in the same patient using special AI software and time-lapse imaging. To join, you must be a woman between 18 and 47 years old, have adequate ovarian reserves (AMH level), and be willing to undergo two IVF (in vitro fertilization) cycles and PRP treatment. The main goal is to see if PRP improves blastocyst formation and embryo quality after one year.

Study design
This is an interventional study planning to enroll 180 women. It is not specified if it is randomized or blinded.
What's involved
You will undergo an initial IVF cycle, followed by two ovarian PRP injections and a second IVF cycle. Embryo development will be analyzed using AI software.
Compensation
Not stated in the trial record.
Follow-up
Embryo quality will be measured at 1 year after treatment.

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NCT07020546

Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score

Recruiting
NAAges 18–47InterventionalTreatment
Generation Next Fertility
~180 participants
Updated 2025-07-09 on ClinicalTrials.gov
What's tested:Ovarian Platelet-rich plasma (PRP) injections

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Blastocyst formation and embryo quality
Measured over 1 year
Infertility
Poor Ovarian Reserve
Embryo Growth Disorder
in Vitro Fertilization
1 sites across 1 states
New York1
  • Jesse Hade, MD · PRINCIPAL_INVESTIGATOR · Generation Next Fertility

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Eligibility criteria

Inclusion

No none contraindications to IVF or PRP treatment
Adequate ovarian reserves and AMH level
Willingness to undergo two IVF cycles and oPRP treatment

Exclusion

Anovulation due to menopause or perimenopause
Any health conditions that are contraindicated for IVF or oPRP treatment
  • Blastocyst formation and embryo quality1 year

    The number of high quality embryos that are created per cycle