This study is testing if a simpler, less invasive test called the Esophageal String Test (EST) can accurately diagnose Eosinophilic Esophagitis (EoE), a condition causing inflammation in the esophagus (the tube that moves food to your stomach). Currently, EoE is diagnosed using an endoscopy, which is a more involved procedure. Researchers want to see if the EST, which collects fluid from your upper digestive tract, can be a good alternative. You may be able to join if you are 18-65 years old, have trouble swallowing (dysphagia) or a history of food getting stuck, and were born in Africa or have parents born in Africa. The study will determine how well the EST identifies EoE compared to current methods.

Study design

This is an interventional study planning to enroll 70 participants. Participants in the U.S. and Mali will have an Esophageal String Test (EST) before a planned endoscopy.

What's involved

You will be screened, provide blood, stool, urine, and skin swab samples, and complete questionnaires. An Esophageal String Test will be performed before your endoscopy.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint is measured at the end of the study, but specific follow-up duration is not detailed.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.