NCT07029165

Kidney Blood Flow During Exercise in Older African American Adults

Active, Not Recruiting
NAAges 55–79InterventionalBasic science
University of Massachusetts, Boston
~12 participants
Updated 2026-07-15 on ClinicalTrials.gov
What's tested:Acute exerciseCold pressor testMental stress test

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in renal vascular resistance during acute exercise
Measured over Pre-acute exercise and during 5 minutes of steady-state exercise
+2 more outcomes measured
Healthy
1 sites across 1 states
Massachusetts1
  • Rachel C Drew, PhD · PRINCIPAL_INVESTIGATOR · University of Massachusetts, Boston

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Self-report as either African American or White racial identity
Born in United States
Both biological parents identify as same racial identity as participant
Recreationally active (participating in physical activity for at least 20 minutes per day, at least three times per week, but not training for competitive events)
Fluent in English

Exclusion

Hispanic or Latino
Females who are pregnant or lactating
Cardiovascular or renal disease
Hypertension (blood pressure of more than or equal to 130/80 mmHg)
Diabetes
Obesity (body mass index of more than or equal to 30 kg/m2)
Smoker/Tobacco user
Acute medical conditions
Taking prescribed cardiovascular, antihypertensive, or renal medications
  • Change in renal vascular resistance during acute exercisePre-acute exercise and during 5 minutes of steady-state exercise

    For the acute exercise intervention, the percent change from pre-acute exercise to during steady-state exercise will be assessed.

  • Change in renal vascular resistance during cold pressor testPre-cold pressor test to after 30, 60, 90, and 120 seconds of cold pressor test

    For the cold pressor test intervention, the percent change from pre-cold pressor test to 30-second intervals during the cold pressor test will be assessed.

  • Change in renal vascular resistance during mental stress testPre-mental stress test to after 1, 2, 3, 4, and 5 minutes of mental stress test

    For the mental stress test intervention, the percent change from pre-mental stress test to 1-minute intervals during the mental stress test will be assessed.