Reset: Enhancing Weight Loss in a Digital Intervention

The Reset study is looking for adults who are overweight or have obesity and are interested in losing weight through behavioral changes. This 12-week digital program aims to find the best combination of strategies to help with weight loss. All participants will receive a core program with daily weight monitoring, weekly lessons on healthy eating and activity, and personalized feedback. Some participants will also focus on limiting "Red Zone Foods" (high-calorie, low-nutrition foods), limiting their eating window (time-restricted eating), increasing protein, or increasing fiber intake. The main goal is to see how much weight participants lose after 3 months.

Study design
This is an interventional study planning to enroll 208 adult participants. It is designed to compare different dietary behavior strategies within a digital weight loss program.
What's involved
Participants will engage in a 12-week digital intervention, including daily self-monitoring of weight and, for some, daily self-monitoring of specific dietary behaviors.
Compensation
Not stated in the trial record.
Follow-up
Weight change will be measured at Baseline and 3 Months.

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NCT07032571

Reset: Enhancing Weight Loss in a Digital Intervention

Not Yet Recruiting
NAAges 18+InterventionalTreatment
Stanford University
~208 participants
Updated 2026-08-04 on ClinicalTrials.gov
What's tested:Core Behavioral Weight Loss InterventionLimit Red Zone FoodsLimit Eating WindowIncrease ProteinIncrease Fiber Intake

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Weight Change from Baseline to 3 Months
Measured over Baseline and 3 Months
Obesity
Overweight
Weight Loss
Health Behavior
Lifestyle Intervention
1 sites across 1 states
California1
  • Michele L Patel, PhD · PRINCIPAL_INVESTIGATOR · Stanford University

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Eligibility criteria

Inclusion

adults (ages 18+ years)
body mass index (BMI) 25.0 to 45.0 kg/m\^2
cellphone ownership with a texting plan
daily access to a personal scale
daily access to a personal email account
English language proficiency
interest in losing weight through behavioral strategies
living in the United States

Exclusion

concurrent enrollment in another weight management intervention
loss of ≥5% body weight in the past 6 months
current use of a weight loss or anti-obesity medication
prior or planned bariatric surgery in the next 3 months
current pregnancy, planned pregnancy in the next 3 months, or recent pregnancy in the past 6 months
current breastfeeding or lactating
living with someone else participating in the study
hospitalization for a mental health condition in the past 12 months
inability to engage in moderate forms of physical activity akin to brisk walking
if weight loss is contraindicated or might be impacted by a condition (e.g., end stage renal disease, cancer, schizophrenia, dementia) or medication (e.g., steroids, antipsychotics)
if an individual would be better suited for a more intensive or different type of intervention based on a health condition (e.g., individuals with history of an eating disorder or cardiovascular event, uncontrolled hypertension, or uncontrolled diabetes mellitus)
participation in another weight loss study conducted in Dr. Patel's lab in the past 6 months
investigator discretion for safety reasons
  • Weight Change from Baseline to 3 MonthsBaseline and 3 Months

    mean change in kg; assessed via participants' personal scales