SNaP Device for Lower Limb Wound Healing After Mohs Surgery

This study is looking at whether a disposable negative pressure wound therapy (dNPWT) device called SNaP helps lower limb wounds heal faster after Mohs micrographic surgery (a precise surgery for skin cancer). Mohs surgery can leave wounds, especially on the lower limbs. Researchers want to compare the SNaP device to standard wound care. You might be able to join if you are 19-79 years old, have a lower limb wound from Mohs surgery for non-melanoma skin cancer that is less than 13 cm x 13 cm, and can change the SNaP system at home. The main goal is to see how long it takes for your wound to heal, measured for up to 12 weeks. The current recruitment status is unclear.

Study design
This study plans to enroll 60 participants and will randomly assign them to one of two groups: either using the SNaP device or receiving standard wound care.
What's involved
You would attend weekly follow-up visits for up to 12 weeks, where the SNaP device would be re-applied or your standard dressing changed. You would also receive education on how to manage your wound care at home.
Compensation
Not stated in the trial record.
Follow-up
After your study intervention is complete, you will have a follow-up at week 12.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07032701

A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer

Not Yet Recruiting
NAAges 19–79InterventionalSupportive care
Jonsson Comprehensive Cancer Center
~60 participants
Updated 2026-07-01 on ClinicalTrials.gov
What's tested:Best PracticeEducational InterventionElectronic Health Record ReviewFollow-Up CareMedical Device Usage and EvaluationNegative Pressure Wound Therapy

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Wound healing duration
Measured over Up to 12 weeks
Skin Carcinoma

NCT07032701

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • UCLA / Jonsson Comprehensive Cancer Center

    Los Angeles, Californiastudy coordinator listed

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Jeremy C Davis · PRINCIPAL_INVESTIGATOR · UCLA / Jonsson Comprehensive Cancer Center

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Eligibility criteria

Inclusion

Aged 19 to 79 years
Presenting with a lower limb wound following Mohs surgery for non-melanoma skin cancer, designated to heal by secondary intention
Wound size less than 13 cm x 13 cm
Patient capable of changing the SNAP-therapy system at home

Exclusion

History of diabetes mellitus
History of venous insufficiency
History peripheral arterial disease
Chronic steroid use (defined as great than 6 weeks) within the last one year
History of HIV
History of chemotherapy use within the last one year
History of smoking exceeding 10 pack-years or current smoker
History of stroke
History of deep venous thrombosis
Active infection
Allergy to adhesives
Wounds with visible bone, tendon, ligament, nerve
  • Wound healing durationUp to 12 weeks

    Will be defined as the number of days from surgery to complete wound closure (full re-epithelialization), assessed during follow-up visits. Will be analyzed as a time-to-event variable. To compare the time to wound closure between the SNaP Wound Care System (Ultraportable Mechanically Powered Negative Pressure Wound Therapy) (SNaP) device and standard care groups, Kaplan-Meier survival curves will be generated, which will visually illustrate whether the SNaP device accelerates wound healing. The log-rank test will be used to formally assess whether the difference in healing times between the two groups is statistically significant or if any differences observed could have arisen by random chance. Additionally, a Multivariable Cox proportional hazards model will be employed to adjust for potential confounders (e.g., wound size, patient age, and comorbidities).