Spironolactone for High Blood Pressure After Pregnancy
This study is looking at whether a medication called spironolactone can help women who had high blood pressure during pregnancy (preeclampsia or gestational hypertension) to lower their blood pressure after delivery. You might be able to join if you are at least 18 years old, had high blood pressure during pregnancy, and had a BMI of 25 or higher before or early in your pregnancy. Participants will receive either 25 mg of spironolactone or a placebo (an inactive pill) once a day for 12 weeks after delivery. The main goal is to see if spironolactone helps reduce your average blood pressure measured over 24 hours at 36 weeks after delivery. The study is currently unclear on its recruitment status and plans to enroll 204 women.
- Study design
- This is an interventional study comparing spironolactone to a placebo. It plans to enroll 204 participants.
- What's involved
- Participants will take a study medication daily for 12 weeks. Blood pressure will be measured at 36 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured at 36 weeks after delivery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories
At a glance
Conditions
Where it's being run
3 sites across 2 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Mean 24-hour ambulatory diastolic blood pressure36 weeks
24-hour BP monitoring will be performed as part of end-of-study assessments using a validated ambulatory BP monitor.