A Study of SBO-154 for Advanced Solid Tumors

This study is testing a drug called SBO-154 in people with advanced solid tumors (cancers that start in organs like the breast, lung, or colon). You might be able to join if your cancer has not responded to standard treatments or you can't tolerate them. The main goals are to see how safe SBO-154 is, what side effects it might cause, and to find the highest dose that can be given safely. The study is looking for 177 participants and involves giving SBO-154 intravenously (into a vein) every three weeks. This is a Phase 1 study, meaning it's one of the first times SBO-154 is being tested in humans.

Study design
This is a Phase 1 interventional study with a planned enrollment of 177 participants. It has two parts, first to find a safe dose and then to evaluate safety in specific cancer types.
What's involved
You would need to attend scheduled visits, follow a treatment plan, and undergo laboratory testing and study procedures. You would receive SBO-154 intravenously every 3 weeks.
Compensation
Not stated in the trial record.
Follow-up
You will be followed for treatment-related serious adverse events and adverse events throughout the study, up to 30 days after your last dose of SBO-154.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT07042100

A Study to Test the Safety and Tolerability of SBO-154 in Patients With Advanced Solid Tumors.

Recruiting
PHASE1Ages 18+InterventionalTreatment
Sun Pharma Advanced Research Company Limited
~177 participants
Updated 2026-07-28 on ClinicalTrials.gov
What's tested:Dose level (DL)1DL2DL3DL4DL5

At a glance

Recruiting sites
12 of 16 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of dose-limiting toxicities
Measured over Twenty-one days from the initiation of the first dose of SBO-154 (3 weeks)
+2 more outcomes measured
Advanced Solid Tumors

NCT07042100

Where you'd take part

This study runs at 16 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • All India Institute for Medical Sciences

    Delhi, New Delhi, Indiastudy coordinator listed

    Recruiting

  • Amrita Institute of Medical Sciences

    Ernākulam, Kerala, Indiastudy coordinator listed

    Not yet recruiting

  • Cancer Research South Australia

    Adelaide, South Australia, Australiastudy coordinator listed

    Recruiting

  • Honorhealth Research Institute

    Scottsdale, Arizonastudy coordinator listed

    Recruiting

  • Hope and Healing Clinical Research LLC

    Hinsdale, Illinoisstudy coordinator listed

    Recruiting

  • Kainos Super Speciality Hopsital

    Rohtak, Haryana, Indiastudy coordinator listed

    Not yet recruiting

  • MD Anderson Cancer Center

    Houston, Texasstudy coordinator listed

    Recruiting

  • Noble Hospital Pvt. Ltd.

    Pune, Maharashtra, Indiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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  • Incidence of dose-limiting toxicitiesTwenty-one days from the initiation of the first dose of SBO-154 (3 weeks)

    Applicable to Part 1 only

  • Incidence of treatment-related serious adverse eventsThroughout the study: from the start of study drug to 30 days post the last dose of study drug.
  • Incidence of treatment-related adverse eventsThroughout the study: from the start of study drug to 30 days post the last dose of study drug.